{"title":"Top Seller","description":"","products":[{"product_id":"yesnutri-probiotics-plus-spirulina","title":"YesNutri Probiotics Plus Spirulina","description":"\u003cul\u003e\n\u003cli\u003e\u003cspan class=\"\"\u003eMaintain gastrointestinal health\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan class=\"\"\u003ePromote defecation, eliminate toxins\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan class=\"\"\u003ePromote intestinal immunity, improve ingestion\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan class=\"\"\u003eRelieve intestinal irritation\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan class=\"\"\u003eEliminate bad breath and skin problem\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan class=\"\"\u003eResistant to gastric acid and bile, effectively colonizing the intestinal tract and enhancing the survival rate of the microbiota[1].\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eProduct Introduction\u003c\/h3\u003e\n\u003cp\u003eYesNutri Probiotics Plus Spirulina consists of two natural probiotics, which help maintain gastrointestinal and digestive function health. Majority of urbanite may have gastrointestinal problems and this formula can help improve gastrointestinal health. Probiotics can balance microflora in the gastrointestinal tract, as a result to promote gastrointestinal health, protect against bad bacteria, relieve symptoms of allergy, and assists in digestion. Spirulina can help clear the way of the digestive tract and enhance nutrient absorption in the intestine. In addition, spirulina possesses detoxification power to reduce damage to kidney by drugs and heavy metals.\u003c\/p\u003e\n\u003ch3\u003eProduct Name\u003c\/h3\u003e\n\u003cp\u003eYesNutri Probiotics Plus Spirulina\u003c\/p\u003e\n\u003ch3\u003ePack Size\u003c\/h3\u003e\n\u003cp\u003e60 Tablets\u003c\/p\u003e\n\u003ch3\u003ePlace of Origin\u003c\/h3\u003e\n\u003cp\u003eAmerica\u003c\/p\u003e\n\u003ch3\u003eComposition\u003c\/h3\u003e\n\u003cp\u003eEach tablet contains:\u003c\/p\u003e\n\u003cp\u003eL-Acidophilus (LA-14) 500 million CFU\u003cbr\u003eSpirulina 500mg\u003c\/p\u003e\n\u003ch3\u003eDirection\u003c\/h3\u003e\n\u003cp\u003eAdults take 2 tablets 2 times daily.\u003c\/p\u003e\n\u003cp\u003eChildren aged 6 and above take 1 tablet 2 times daily or as directed by physicians.\u003c\/p\u003e\n\u003ch3\u003eDescription\u003c\/h3\u003e\n\u003ch4\u003eProbiotics Maintain Balance of Gut Microflora\u003c\/h4\u003e\n\u003cp\u003eThe Food and Agriculture Organization of the United Nations and the World Health Organization defined probiotics as \"Live microorganisms which when administered in adequate amounts confer a health benefit on the host\". Probiotics (derived from Greek, meaning \"for life\") are live microorganisms that help balance intestinal microflora and improve health. Most often, the bacteria come from two groups, Lactobacillus or Bifidobacterium. Their main functions include:\u003c\/p\u003e\n\u003ch4\u003eMaintain Gastrointestinal Health\u003c\/h4\u003e\n\u003cp\u003eProbiotics can improve the digestion problems in children. The role of probiotics is closely related to the development of many gastroenterology problems. Some strains resist to acid and adhere to the cell wall of the stomach. They reduce the growth of bacteria which may cause digestion problems.\u003c\/p\u003e\n\u003ch4\u003eDefense against Bacteria\u003c\/h4\u003e\n\u003cp\u003eSome strains of probiotics could acidify the urogenital system. It helps suppress the growth of pathogens. The \"good\" bacteria kick out the \"bad\" bacteria by competing for spaces and resources for colonization. Probiotics produce organic acids, free fatty acids, hydrogen peroxide, and bacteriocins. These can aid to defense against pathogens.\u003c\/p\u003e\n\u003ch4\u003eAlleviate Symptoms of Allergy \u0026amp; Break Down of Lactose\u003c\/h4\u003e\n\u003cp\u003eProbiotics regulate the level of immunoglobulin E (IgE) to reduce the allergic symptoms. Researches show that they can manage dermatology problems. Probiotics assist in gastrointestinal digestion by converting lactose to lactic acid.\u003c\/p\u003e\n\u003ch4\u003eThe Roles of Lactobacillus acidophilus:\u003c\/h4\u003e\n\u003cp\u003eThe Lactobacillus acidophilus in the formula is of vital importance for human health. It can regulate the balance of the intestinal flora, enhance intestinal immunity, and exhibit antibacterial activity against various pathogenic bacteria. Lactobacillus acidophilus can grow stably at relatively low pH values (below pH 5.0), thus effectively surviving in gastric acid and increasing its survival rate in the stomach, ensuring its effective colonization in the intestinal tract and maintaining its activity after reaching the gastrointestinal tract.\u003csup\u003e1,2\u003c\/sup\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eIt can produce organic acids such as acetic acid and lactic acid, which are conducive to inhibiting the growth of pathogenic bacteria, maintaining a healthy intestinal environment, regulating the balance of the intestinal flora, and enhancing immunity.\u003csup\u003e1,2\u003c\/sup\u003e\n\u003c\/li\u003e\n\u003cli\u003eIt can serve as a source of lactase in the small intestine, assisting people with lactose intolerance in metabolizing lactose, thereby reducing intestinal discomfort symptoms such as diarrhea caused by lactose intake.\u003csup\u003e1,2\u003c\/sup\u003e\n\u003c\/li\u003e\n\u003cli\u003eIt can increase the production of pepsinogen, thereby effectively accelerating and improving gastric digestion capacity.\u003csup\u003e3\u003c\/sup\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch4\u003eNutritious Spirulina for Multiple Benefits\u003c\/h4\u003e\n\u003cp\u003eSpirulina are a large number of cyanobacteria or blue-green algae. These algae are found in warm, alkaline waters around the world, especially of Mexico and Central Africa. The nutritional values of Spirulina have drawn attention over a few decades:\u003c\/p\u003e\n\u003cp\u003e– Contain high content of protein (60-70%), a source of many types of essential amino acids\u003cbr\u003e– Consist of multivitamins, especially B12 and β-carotene. β-carotene is an antioxidant which could suppress the damage to cells by free radicals, slowing down aging. In human body, β-carotene is converted to pro-vitamin A which has beneficial effects to the eyes and skin.\u003cbr\u003e– Rich in minerals, such as iron, magnesium and calcium\u003cbr\u003e– Serve as a source for high content of EPA and gamma-linoleic acid\u003cbr\u003e– Compose high content of DNA and RNA. Spirulina also contains phycocyanin. When combined with chlorophyll, they become antioxidants.\u003c\/p\u003e\n\u003ch4\u003eReference\u003c\/h4\u003e\n\u003col\u003e\n\u003cli\u003eGao, H., Li, X., Chen, X., Hai, D., Wei, C., Zhang, L., \u0026amp; Li, P. (2022). The Functional Roles of Lactobacillus acidophilus in Different Physiological and Pathological Processes. Journal of microbiology and biotechnology, 32(10), 1226–1233. https:\/\/doi.org\/10.4014\/jmb.2205.05041\u003c\/li\u003e\n\u003cli\u003eLiu, Y., Nawazish, H., Farid, M. S., Abdul Qadoos, K., Habiba, U. E., Muzamil, M., Tanveer, M., Sienkiewicz, M., Lichota, A., \u0026amp; Łopusiewicz, Ł. (2024). Health-Promoting Effects of Lactobacillus acidophilus and Its Technological Applications in Fermented Food Products and Beverages. Fermentation, 10(8), 380. https:\/\/doi.org\/10.3390\/fermentation10080380\u003c\/li\u003e\n\u003cli\u003eTursi, F., Benedetto, E., Spina, A., De Ponti, I., Amone, F., \u0026amp; Nobile, V. (2024). Efficacy of a Food Supplement Containing Lactobacillus acidophilus LA14, Peptides, and a Multivitamin Complex in Improving Gastroesophageal Reflux Disease-Related Outcomes and Quality of Life of Subjects Showing Mild-to-Moderate Gastroesophageal Reflux Disease. Nutrients, 16(11), 1759. https:\/\/doi.org\/10.3390\/nu16111759\u003c\/li\u003e\n\u003c\/ol\u003e","brand":"YesNutri \/ Beauty and Nutrition","offers":[{"title":"No outer boxes","offer_id":47071076941975,"sku":null,"price":268.0,"currency_code":"HKD","in_stock":true},{"title":"Require outer box (it will be provided if available)","offer_id":47071076974743,"sku":null,"price":268.0,"currency_code":"HKD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0721\/2980\/6487\/files\/YesNutri_BN001_Piobiotics_Plus_Spirulina_60s_main1-scaled.jpg?v=1772866769"},{"product_id":"yesnutri-12-probiotics-sachets","title":"YesNutri 12 Probiotics Sachets","description":"\u003cul\u003e\n\u003cli\u003e\u003cspan class=\"\"\u003eStrengthen gastrointestinal health\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan class=\"\"\u003ePromotes bowel movements and reduces gut discomfort for kids\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan class=\"\"\u003eImprove and maintain children's natural immune defense\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan class=\"\"\u003eRelieve sensitivity and indigestion\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan class=\"\"\u003eResistant to gastric acid and bile, effectively colonizing the intestinal tract and\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan class=\"\"\u003eenhancing the survival rate of the microbiota.\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eProduct Introduction\u003c\/h3\u003e\n\u003cp\u003eYesNutri 12 Probiotics consists of 12 different kinds of probiotics, rich in a variety of bifidobacterium and lactobacillus. It can increase intestinal probiotics while inhibiting the growth of harmful bacteria. It helps restore healthy microflora balance in the gastrointestinal tract to maintain natural immune defense for kids. Also, it is beneficial to children's bowel movements and prevents constipation.\u003c\/p\u003e\n\u003ch3\u003eProduct Name\u003c\/h3\u003e\n\u003cp\u003eYesNutri 12 Probiotics\u003c\/p\u003e\n\u003ch3\u003ePack Size\u003c\/h3\u003e\n\u003cp\u003e15\/ 30 sachets\u003c\/p\u003e\n\u003ch3\u003ePlace of Origin\u003c\/h3\u003e\n\u003cp\u003eKorea\u003c\/p\u003e\n\u003ch3\u003eComposition\u003c\/h3\u003e\n\u003cp\u003eEach sachet contains:\u003c\/p\u003e\n\u003cp\u003e12 kinds of probiotics: 10 billion CFU (Lactobacillus plantarum, lactobacillus rhamnosus, lactobacillus fermentum, lactobacillus casei, bifidobacterium breve, lactobacillus salivarius, bifidobacterium bifidum, lactobacillus acidophilus, lactobacillus paracasei, bifidobacterium longum, streptococcus thermophiles, lactobacillus helveticus)\u003c\/p\u003e\n\u003cp\u003eGlucose, xylitol, skim milk powder, vegetable cream powder (starch syrup, processed palm oil, sodium caseinate, emulsifier (331,340(ii), 452(i)) and glycerin esters of fatty acids), dextrin, fructooligosaccharide, flavor (orange extract concentrated powder), lactobacillus mixed powder (lactobacillus plantarum, lactobacillus rhamnosus, lactobacillus fermentum, lactobacillus casei, bifidobacterium breve, lactobacillus salivarius, bifidobacterium bifidum, lactobacillus acidophilus, lactobacillus paracasei, bifidobacterium longum, streptococcus thermophiles, lactobacillus helveticus and potato starch), emulsifier (460), anticaking agent (551), acidity regulator (330), mixed fruit extract (orange, mango, passionfruit, guava and banana), antioxidant(ascorbic acid), colostrum powder, mixed vegetable extract powder (cauliflower extract, cucumber extract, sweet pumpkin extract, cabbage extract, buttercup extract, kale extract, parsley extract, red pepper extract, green pepper extract, red beet extract, broccoli extract), zinc oxide, pyridoxine hydrochloride, riboflavin, thiamine hydrochloride\u003c\/p\u003e\n\u003ch3\u003eDirection\u003c\/h3\u003e\n\u003cp\u003eTake 1-2 sachets directly daily; or mix with cold water, milk or other liquid food to take.\u003c\/p\u003e\n\u003ch3\u003eThe Roles of Lactobacillus acidophilus:\u003c\/h3\u003e\n\u003cp\u003eThe Lactobacillus acidophilus in the formula is of vital importance for human health. It can regulate the balance of the intestinal flora, enhance intestinal immunity, and exhibit antibacterial activity against various pathogenic bacteria. Lactobacillus acidophilus can grow stably at relatively low pH values (below pH 5.0), thus effectively surviving in gastric acid and increasing its survival rate in the stomach, ensuring its effective colonization in the intestinal tract and maintaining its activity after reaching the gastrointestinal tract.\u003csup\u003e1,2\u003c\/sup\u003e\u003c\/p\u003e\n\u003cp\u003eIt can produce organic acids such as acetic acid and lactic acid, which are conducive to inhibiting the growth of pathogenic bacteria, maintaining a healthy intestinal environment, regulating the balance of the intestinal flora, and enhancing immunity.\u003csup\u003e1,2\u003c\/sup\u003e\u003cbr\u003eIt can serve as a source of lactase in the small intestine, assisting people with lactose intolerance in metabolizing lactose, thereby reducing intestinal discomfort symptoms such as diarrhea caused by lactose intake.\u003csup\u003e1,2\u003c\/sup\u003e\u003cbr\u003eIt can increase the production of pepsinogen, thereby effectively accelerating and improving gastric digestion capacity.\u003csup\u003e3\u003c\/sup\u003e\u003c\/p\u003e\n\u003ch4\u003eReference\u003c\/h4\u003e\n\u003col\u003e\n\u003cli\u003eGao, H., Li, X., Chen, X., Hai, D., Wei, C., Zhang, L., \u0026amp; Li, P. (2022). The Functional Roles of Lactobacillus acidophilusin Different Physiological and Pathological Processes. Journal of microbiology and biotechnology, 32(10), 1226–1233. https:\/\/doi.org\/10.4014\/jmb.2205.05041\u003c\/li\u003e\n\u003cli\u003eLiu, Y., Nawazish, H., Farid, M. S., Abdul Qadoos, K., Habiba, U. E., Muzamil, M., Tanveer, M., Sienkiewicz, M., Lichota, A., \u0026amp; Łopusiewicz, Ł. (2024). Health-Promoting Effects of Lactobacillus acidophilus and Its Technological Applications in Fermented Food Products and Beverages. Fermentation, 10(8), 380. https:\/\/doi.org\/10.3390\/fermentation10080380\u003c\/li\u003e\n\u003cli\u003eTursi, F., Benedetto, E., Spina, A., De Ponti, I., Amone, F., \u0026amp; Nobile, V. (2024). Efficacy of a Food Supplement Containing Lactobacillus acidophilus LA14, Peptides, and a Multivitamin Complex in Improving Gastroesophageal Reflux Disease-Related Outcomes and Quality of Life of Subjects Showing Mild-to-Moderate Gastroesophageal Reflux Disease. Nutrients, 16(11), 1759. https:\/\/doi.org\/10.3390\/nu16111759\u003c\/li\u003e\n\u003cli\u003eResistant to gastric acid and bile, effectively colonizing the intestinal tract and enhancing the survival rate of the microbiota.\u003c\/li\u003e\n\u003c\/ol\u003e","brand":"YesNutri \/ Smart Children’s Supplements","offers":[{"title":"15 Sachets \/ No outer boxes","offer_id":47082454417559,"sku":null,"price":168.0,"currency_code":"HKD","in_stock":true},{"title":"15 Sachets \/ Require outer box (it will be provided if available)","offer_id":47082456055959,"sku":null,"price":168.0,"currency_code":"HKD","in_stock":true},{"title":"30 Sachets \/ No outer boxes","offer_id":47082454450327,"sku":null,"price":268.0,"currency_code":"HKD","in_stock":true},{"title":"30 Sachets \/ Require outer box (it will be provided if available)","offer_id":47082456088727,"sku":null,"price":268.0,"currency_code":"HKD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0721\/2980\/6487\/files\/SC012_12-Probiotcs_main.jpg?v=1772887875"},{"product_id":"yesnutri-pro-cardio-health","title":"YesNutri Pro Cardio Health","description":"\u003cul\u003e\n\u003cli\u003e\u003cspan class=\"\"\u003eStrong antioxidant\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan class=\"\"\u003eAccelerate blood circulation, remove waste from body\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan class=\"\"\u003eMaintain cardiovascular health\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan class=\"\"\u003eMay assist in stabilizing blood lipids and cholesterol level\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan class=\"\"\u003eDue to the similar ingredients between red yeast rice and lipid-lowering drugs, individuals who are currently taking lipid-lowering or anticoagulant medications should not concurrently consume products containing red yeast rice to avoid potential overdose and adverse reactions. Please consult a doctor before taking the product.\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eProduct Description\u003c\/h3\u003e\n\u003cp\u003eYesNutri Pro Cardio Health contains high quality Red Yeast Rice, Nattokinase and Coenzyme Q10. These three elements are important to keep healthy heart. Red Yeast Rice can purify blood and support heart health. Coenzyme Q10 acts as antioxidants and reduce free radicals. Nattokinase can promote metabolism, removing waste productsfrom blood vessels. It is suitable for people who are concerned about their cholesterol and cardiovascular health. [1-2]\u003c\/p\u003e\n\u003ch3\u003eProduct Name\u003c\/h3\u003e\n\u003cp\u003eYesNutri Pro Cardio Health\u003c\/p\u003e\n\u003ch3\u003ePack Size\u003c\/h3\u003e\n\u003cp\u003e60 Capsules\u003c\/p\u003e\n\u003ch3\u003ePlace of Origin\u003c\/h3\u003e\n\u003cp\u003eAmerica\u003c\/p\u003e\n\u003ch3\u003eComposition\u003c\/h3\u003e\n\u003cp\u003eEach capsule contains:\u003c\/p\u003e\n\u003cp\u003eRed Yeast Rice 600mg\u003cbr\u003eCoenzyme Q10 30mg\u003cbr\u003eNattokinase 5mg\u003c\/p\u003e\n\u003ch3\u003eDirection\u003c\/h3\u003e\n\u003cp\u003eAdults take 1 tablet twice daily or as directed by physicians.\u003c\/p\u003e\n\u003ch3\u003eDescription\u003c\/h3\u003e\n\u003cp\u003eCholesterol is a waxy, fat-like substance found in foods and produced by our liver. It serves as a source for bile secretion and act as a modulator for the health of blood vessels. Additionally, cholesterol is used to protect nerves, construct cell tissues, and make certain hormones. It is an essential substance required in small quantities for body normal function. However, in high quantities, it can have an adverse effect on our health. [3-4]\u003c\/p\u003e\n\u003ch4\u003eWhat Is Total Cholesterol Level in blood?\u003c\/h4\u003e\n\u003cp\u003eOur cholesterol level is measured in milligrams per deciliter of blood (mg\/dL). Three measures are used to calculate the total cholesterol level:[5]\u003c\/p\u003e\n\u003cp\u003eHDL cholesterol (HDL-C), which is considered the 'good' kind of cholesterol\u003cbr\u003eLDL cholesterol (LDL-C), which is considered the 'bad' kind of cholesterol\u003cbr\u003eTriglyceride level (TG).\u003c\/p\u003e\n\u003ch4\u003eBenefits of Red Yeast Rice:\u003c\/h4\u003e\n\u003cp\u003e\u003cstrong\u003eImprovement of circulation\u003c\/strong\u003e\u003cbr\u003eRed yeast rice is a fermented product of rice that is cultivated with red yeast (Monascus purpureus). It has been used as a medicinal food in Chinese culture for centuries due to its ability to promote blood circulation. Extracts of red yeast rice contain several active ingredients as family of monacolin-related substances, sterols, isoflavones and monounsaturated fatty acids. Monacolin-related substances work by inhibiting the enzyme HMG-CoA reductase, which is involved in cholesterol synthesis. Therefore, this product may assist in stabilizing blood lipids\/cholesterol.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eMaintenance of cardiovascular health\u003c\/strong\u003e\u003cbr\u003eBy purifying blood, red yeast rice extract may help to maintain blood vessel and heart health.[1,11-15]\u003c\/p\u003e\n\u003ch4\u003eBenefits of Coenzyme Q10:\u003c\/h4\u003e\n\u003cp\u003eCoenzyme Q10 is a natural antioxidant found in human body cells that plays a role in delaying the aging process of cells. It has several benefits, including:[2]\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eReduction of free radicals\u003c\/strong\u003e\u003cbr\u003eCoenzyme Q10 helps reduce free radicals caused by factors such as UV light exposure, passive smoking, stress, and an imbalanced diet.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eBoosting cellular metabolism\u003c\/strong\u003e\u003cbr\u003eIt aids in boosting cellular metabolism, which is important for overall cell function and energy production.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eActivation of cell growth\u003c\/strong\u003e\u003cbr\u003eCoenzyme Q10 helps activate cell growth and maintenance, supporting healthy cell regeneration.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eSkin health\u003c\/strong\u003e\u003cbr\u003eIt contributes to keeping the skin youthful and delicate, potentially assisting in maintaining skin health and reducing the signs of aging.\u003c\/p\u003e\n\u003ch4\u003eBenefits of Nattokinase:\u003c\/h4\u003e\n\u003cp\u003eNattokinase is an enzyme produced by the natto bacteria (Bacillus subtilis) through the fermentation of soybeans. As a protease, nattokinase has several benefits, including the following: [16-17,19]\u003c\/p\u003e\n\u003cp\u003ePromotion of circulation and metabolism\u003cbr\u003eNattokinase can help promote circulation and metabolism, supporting overall physiological functions.\u003c\/p\u003e\n\u003cp\u003eImproves blood flow and reduces clotting\u003cbr\u003eThrough a series of transformations, nattokinase activates plasmin, which promotes blood flow. This makes it widely used for maintaining cardiovascular health.\u003c\/p\u003e\n\u003cp\u003eMaintenance of respiratory system health\u003cbr\u003eStudies have shown that taking nattokinase can also reduce blockage of sinus and alleviate symptoms. Nattokinase can reduce excessive mucus and phlegm production in the respiratory tract, making it beneficial for maintaining smooth breathing. It can improve the condition of the respiratory tract, reduce the frequency of symptoms, and decrease the risk of attacks.[18]\u003c\/p\u003e\n\u003ch4\u003eReferences\u003c\/h4\u003e\n\u003col\u003e\n\u003cli\u003eMonascus purpureus (red yeast rice). Altern Med Rev. 2004 Jun;9(2):208-210.\u003c\/li\u003e\n\u003cli\u003eLittarru GP, Tiano L. Clinical aspects of coenzyme Q10: an update. Curr Opin Clin Nutr Metab Care. 2005 Nov;8(6):641-646.\u003c\/li\u003e\n\u003cli\u003eScott M. Grundy. Cholesterol Metabolism in Man. West J Med. 1978 January; 128(1): 13–25.\u003c\/li\u003e\n\u003cli\u003eOlson RE. Discovery of the Lipoproteins, Their Role in Fat Transport and Their Significance as Risk Factors. J. Nutr. 1998 Feb;128(2 Suppl):439S-443S.\u003c\/li\u003e\n\u003cli\u003eFriedewald WT, Levy RI, Fredrickson DS. Estimation of the Concentration of Low-Density Lipoprotein Cholesterolin Plasma,Without Use of the Preparative Ultracentrifuge. Clin Chem. 1972 Jun;18(6):499-502.\u003c\/li\u003e\n\u003cli\u003eHuxley RR, Barzi F, Lam TH, Woodward M, et al. Isolated Low Levels of High-Density Lipoprotein Cholesterol Are Associated With an Increased Risk of Coronary Heart Disease: An Individual Participant Data Meta-Analysis of 23 Studies in the Asia-Pacific Region. Circulation. 2011;124:2056-2064.\u003c\/li\u003e\n\u003cli\u003eNational Heart, Lung, and Blood Institute (NHLBI). Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III) – Executive Summary. May 2001. NIH Publication No. 01-3670. Available at: http:\/\/www.nhlbi.nih.gov\/guidelines\/cholesterol\/atp3xsum.pdf.\u003c\/li\u003e\n\u003cli\u003eGrundy SM, Cleeman JI, Stone NJ et al. ATP III Update 2004: Implications of Recent Clinical Trials for the ATP III Guidelines. Circulation. 2004;110:227-239.\u003c\/li\u003e\n\u003cli\u003eManninen V, Tenkanen L, Koskinen P, Huttunen JK, Manttari M, Heinonen OP, Frick MH. Joint effects of serum triglyceride and LDL cholesterol and HDL cholesterol concentrations on coronary heart disease risk in the Helsinki Heart Study: implications for treatment. Circulation. 1992;85:37-45.\u003c\/li\u003e\n\u003cli\u003eYarnell JWG, Patterson CC, Sweetnam PM, Miller NE, et al. Do total and high-density lipoprotein cholesterol and triglycerides act independently in the prediction of ischemic heart disease?: Ten-year follow-up of Caerphilly and Speedwell cohorts. Arterioscler Thromb Vasc Biol. 2001;21:1340-1345.\u003c\/li\u003e\n\u003cli\u003eHeber D, Yip I, Ashley JM, Elashoff DA, Elashoff RM, Go VL. Cholesterol-lowering effects of a proprietary Chinese red-yeast-rice dietary supplement. Am J Clin Nutr. 1999 Feb;69(2):231-6.\u003c\/li\u003e\n\u003cli\u003eLin CC, Li TC, Lai MM. Efficacy and safety of Monascus purpureusWent rice in subjects with hyperlipidemia. Eur J Endocrinol 2005;153(5):679–686.\u003c\/li\u003e\n\u003cli\u003eShang Q, Liu Z, Chen K, Xu H, Liu J.A systematic review of xuezhikang, an extract from red yeast rice, for coronary heart disease complicated by dyslipidemia. Evid Based Complement Alternat Med. 2012;2012:636547. Epub 2012 Apr 12.\u003c\/li\u003e\n\u003cli\u003eKlimek M, Wang S, Ogunkanmi A. Safety and Efficacy of Red Yeast Rice (Monascus purpureus) as an Alternative Therapy for Hyperlipidemia. P T. 2009 Jun;34(6):313-327.\u003c\/li\u003e\n\u003cli\u003eBecker DJ, Gordon RY, Halbert SC, French B, Morris PB, Rader DJ. Red yeast rice for dyslipidemia in statin-intolerant patients: a randomized trial. Ann Intern Med. 2009;150(12):830-839.\u003c\/li\u003e\n\u003cli\u003eChen H, McGowan EM, Ren N, Lal S, Nassif N, Shad-Kaneez F, Qu X, Lin Y. Nattokinase: A Promising Alternative in Prevention and Treatment of Cardiovascular Diseases. Biomark Insights. 2018 Jul 5;13:1177271918785130.\u003c\/li\u003e\n\u003cli\u003eWeng Y, Yao J, Sparks S, Wang KY. Nattokinase: An Oral Antithrombotic Agent for the Prevention of Cardiovascular Disease. Int J Mol Sci. 2017 Feb 28;18(3):523.\u003c\/li\u003e\n\u003cli\u003eTakabayashi T, Imoto Y, Sakashita M, Kato Y, Tokunaga T, Yoshida K, Narita N, Ishizuka T, Fujieda S. Nattokinase, profibrinolytic enzyme, effectively shrinks the nasal polyp tissue and decreases viscosity of mucus. Allergol Int. 2017 Oct;66(4):594-602.\u003c\/li\u003e\n\u003cli\u003eKurosawa Y, Nirengi S, Homma T, Esaki K, Ohta M, Clark JF, Hamaoka T. A single dose of oral nattokinase potentiates thrombolysis and anticoagulation profiles. Sci Rep. 2015 Jun 25;5:11601.\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003ch4\u003eDisclaimer\u003c\/h4\u003e\n\u003cp\u003eThis product is not registered under the Pharmacy and Poisons Ordinance or the Chinese Medicine Ordinance. Any claim made for it has not been subject to evaluation for such registration. This product is not intended to diagnose, treat or prevent any disease.\u003c\/p\u003e","brand":"YesNutri \/ Cardio and Body Health","offers":[{"title":"No outer boxes","offer_id":47207481049239,"sku":null,"price":549.0,"currency_code":"HKD","in_stock":true},{"title":"Require outer box (it will be provided if available)","offer_id":47207481082007,"sku":null,"price":549.0,"currency_code":"HKD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0721\/2980\/6487\/files\/CB024_Yesnutri_Pro-Cardio-Health__main-1.jpg?v=1773305924"},{"product_id":"yesnutri-eyebright-bilberry-support","title":"YesNutri Eyebright \u0026 Bilberry Support","description":"\u003cul\u003e\n\u003cli\u003e\u003cspan class=\"\"\u003eNourish eyes and retina\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan class=\"\"\u003eRelieve dry eye and tiredness\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan class=\"\"\u003eReduce eye bag and dark circle\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan class=\"\"\u003eBetter and sharper vision\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan class=\"\"\u003eNeutralize free radicals and delay eyes aging\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eProduct Introduction\u003c\/h3\u003e\n\u003cp\u003eYesNutri Eyebright \u0026amp; Bilberry Support is formulated with high quality eyebright and bilberry, supporting with lutein, zeaxanthin, carotenoids and other minerals. Eyebright can relieve eye fatigue and discomfort. It targets at people who sit in front of monitors for long hours and effectively protects the eyes and relieve eye stress. Bilberry extract promotes production of night vision pigments in retina. It helps eyes adapt to light change and provides anti-oxidizing protection with other antioxidants.\u003c\/p\u003e\n\u003ch3\u003eProduct Name\u003c\/h3\u003e\n\u003cp\u003eYesNutri Eyebright \u0026amp; Bilberry Support\u003c\/p\u003e\n\u003ch3\u003ePack Size\u003c\/h3\u003e\n\u003cp\u003e60 Softgel Capsules\u003c\/p\u003e\n\u003ch3\u003ePlace of Origin\u003c\/h3\u003e\n\u003cp\u003eAmerica\u003c\/p\u003e\n\u003ch3\u003eComposition\u003c\/h3\u003e\n\u003cp\u003eEach softgel capsule contains:\u003c\/p\u003e\n\u003cp\u003eBilberry (Vaccinium myrtillus)(from 4:1 Extract) 100mg\u003cbr\u003eDocosahexaenoic Acid(DHA) (from fish oil) 50mg\u003cbr\u003eEyebright (Euphrasia officinalis) (from 4:1 Extract) 100mg\u003cbr\u003eLutein 2mg\u003cbr\u003eZeaxanthin 60mcg\u003cbr\u003eZinc 900mcg\u003cbr\u003eCopper 200mcg\u003c\/p\u003e\n\u003ch3\u003eDirection\u003c\/h3\u003e\n\u003cp\u003eChildren aged 6 or above: take 1 softgel capsule daily after meal;\u003c\/p\u003e\n\u003cp\u003eAdults and children aged 12 or above :take 1 softgel capsule twice daily after meal: or as directed by physicians.\u003c\/p\u003e\n\u003ch3\u003eDescription\u003c\/h3\u003e\n\u003cp\u003eThe following ingredients may help to relieve symptoms of eye discomfort:\u003c\/p\u003e\n\u003ch4\u003eEyebright Extract\u003c\/h4\u003e\n\u003cp\u003eEyebright, also called Euphrasia, is a flowering herb that contains iridoid glycosides, euphroside and phenylpropanoid glycosides. Diabetic retinopathy, a leading cause of blindness worldwide, is one of the major complications in patients with diabetes. Fluxes of glucose into retinal cells may pose strong oxidative stress and induce inflammatory response of the cells, resulting in retinal damage. By reducing blood glucose level, it may help lower the risk of the disease. Eyebright extract could also be used in eye-drops to directly relieve tear film inflammation.\u003c\/p\u003e\n\u003ch4\u003eBilberry Extract\u003c\/h4\u003e\n\u003cp\u003eBilberry extract contains anthocyanins (a flavonoid) and ascorbic acid (one form of vitamin C). Flavonoids possess neuroprotective and anti-oxidizing properties. It is believed that anthocyanins could therefore help to protect the retina, the nerve layer that lines the back of our eyes sending nerve impulses to the visual area of our brain. Anthocyanins could also boost the production of rhodopsin, the pigment responsible for night vision and helps our eyes adapt to light change. Together with other antioxidants in the formula, i.e. beta carotene, vitamins C \u0026amp; E, the constituents could provide protection to the eyes against oxidative stress and maintain healthy nerves for light sensation.\u003c\/p\u003e\n\u003ch4\u003eLutein \u0026amp; Zeaxanthin\u003c\/h4\u003e\n\u003cp\u003eLutein and zeaxanthin are natural carotenoids which can be found in the macula and the rest of the retina. Lutein and zeaxanthin could not be synthesized in mammals, and must be obtained from the diet. These two compounds are yellowish pigments which could filter blue light at the high energy end of the visible spectrum, thus reducing UV radiation toxicity to the retina and the skin.\u003c\/p\u003e","brand":"YesNutri \/ Personal Care Products","offers":[{"title":"30-softgel-capsules \/ No outer boxes","offer_id":47293030400151,"sku":null,"price":168.0,"currency_code":"HKD","in_stock":true},{"title":"30-softgel-capsules \/ Require outer box (it will be provided if available)","offer_id":47880626897047,"sku":null,"price":168.0,"currency_code":"HKD","in_stock":true},{"title":"60-softgel-capsules \/ No outer boxes","offer_id":47293030432919,"sku":null,"price":268.0,"currency_code":"HKD","in_stock":true},{"title":"60-softgel-capsules \/ Require outer box (it will be provided if available)","offer_id":47880626929815,"sku":null,"price":268.0,"currency_code":"HKD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0721\/2980\/6487\/files\/YesNutri_PC001_Eyebright_Bilberry_Support_60sc_main.jpg?v=1780022546"},{"product_id":"yesnutri-kids-growth-calcium-chewable-tablets","title":"YesNutri Kids Growth Calcium Chewable Tablets","description":"\u003cul\u003e\n\u003cli\u003e\u003cspan class=\"\"\u003eKids and teenagers formula\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan class=\"\"\u003ePromotes the healthy growth of bones and teeth\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan class=\"\"\u003eSupport muscle coordination and strength\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan class=\"\"\u003eIncrease attentiveness and concentration\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan class=\"\"\u003eVitamin D enhances calcium absorption\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan class=\"\"\u003eAssists the immune system to fight against pathogens.\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eProduct Introduction\u003c\/h3\u003e\n\u003cp\u003eYesNutri Kids Growth Calcium Chewable Tablets are especially formulated to promote the growth and maintenance of healthy bones and teeth, helping you to grow taller and stronger. Calcium helps to develop strong bones \u0026amp; teeth, and vitamin D enhances its absorption; magnesium is an element that is present chiefly in the bones, and both calcium and magnesium are necessary for the health of our bones \u0026amp; muscles, while zinc is a trace element that is essential for normal growth. Vitamin C is necessary to maintain healthy skin, blood vessels, bones and cartilage.\u003c\/p\u003e\n\u003ch3\u003eProduct Name\u003c\/h3\u003e\n\u003cp\u003eYesNutri Kids Growth Calcium Chewable Tablets\u003c\/p\u003e\n\u003ch3\u003ePack Size\u003c\/h3\u003e\n\u003cp\u003e60 Chewable Tablets\u003c\/p\u003e\n\u003ch3\u003ePlace of Origin\u003c\/h3\u003e\n\u003cp\u003eU.S.A.\u003c\/p\u003e\n\u003ch3\u003eComposition\u003c\/h3\u003e\n\u003cp\u003eEach tablet contains:\u003c\/p\u003e\n\u003cp\u003eCalcium (as Calcium Carbonate) 120mg\u003cbr\u003eMagnesium (as Magnesium Oxide) 25mg\u003cbr\u003eVitamin C (Ascorbic Acid) 10mg\u003cbr\u003eZinc (as Zinc Oxide) 3mg\u003cbr\u003eVitamin D3 (Cholecalciferol) 100IU\u003c\/p\u003e\n\u003ch3\u003eDirections\u003c\/h3\u003e\n\u003cp\u003e1-3 years: take 1 tablets daily;\u003cbr\u003e4-10 years: take 2 tablets daily;\u003cbr\u003e11 years or above and adult: take 3 tablets daily;\u003cbr\u003eor as recommended by physicians.\u003c\/p\u003e\n\u003ch3\u003eDescription\u003c\/h3\u003e\n\u003ch4\u003eMagnesium for Strength\u003c\/h4\u003e\n\u003cp\u003eMagnesium is an important element in the formation of bones and teeth. Magnesium regulates the body's cell growth, energy production, protein synthesis, muscle function and nerve transmission. Some studies have shown that low magnesium level may be associated with attention deficit hyperactivity disorder (ADHD) in children.\u003cbr\u003eMagnesium is involved in bone formation and influences the activities of bone cells. Magnesium can convert vitamin D to its active form which increases calcium absorption. Magnesium can also improve physical performance as it is re-distributed within the body to cater for increased energy need for the muscles.\u003cbr\u003eChildren absorb adequate magnesium to promote healthy development of bones and teeth, strengthen their concentration and enhance the immune system. For adults and the elderly, adequate magnesium intake can strengthen their muscles and bones. It can also maintain the bone activity in optimum level and reduces bone loss. Magnesium can help maintain healthy heart and relieve nervous tension or stress.\u003c\/p\u003e\n\u003ch4\u003eCalcium for Strong Bones\u003c\/h4\u003e\n\u003cp\u003eCalcium is an essential mineral for development of healthy bones. Adequate calcium intake is required in every stage. During childhood and adolescence, maintaining adequate amount of calcium is necessary for healthy development of bones and teeth. With the influence of long working hours and modern dietary culture, adults, especially for those who intake too much caffeine (e.g. from coffee or soft drink), are more difficult to absorb adequate amount of calcium and thus highly increase the risk of bone loss. For people of post-middle age, especially women, their bone density will decrease gradually due to the calcium loss from the bones. The risk of bone fracture and osteoporosis will increase as the bone density decline. Therefore, maintaining adequate calcium absorption is necessary for all age groups to ensure normal bone density and reduce the risk of bone loss.\u003c\/p\u003e\n\u003ch4\u003eZinc for Immunity and Health\u003c\/h4\u003e\n\u003cp\u003eZinc is the human body to maintain healthy essential trace elements. Zinc is important for children's growth and development, neurological function and maintenance of the immune system. Zinc can promote wound healing and activate white blood cells, helping the body to be more effective to fight against infection. Zinc is a strong antioxidant which can protect the eyes. Some studies indicated that zinc deficiency has been linked to depression, learning disabilities and poor attention.\u003cbr\u003eZinc is an important component for the development of bone cells as well. It stimulates bone formation and inhibits bone resorption. Therefore, zinc can increase the bone density and strengthen structure of the bones.\u003cbr\u003eZinc provides comprehensive care for growth and development of children, including IQ, knowledge, language, communication and immunity. Zinc also provides protection for adults and the elderly. Zinc not only can activate the immune system, but also catalyze the formation of new cells which will delay aging.\u003c\/p\u003e\n\u003ch4\u003eVitamin C for the Immune System\u003c\/h4\u003e\n\u003cp\u003eVitamin C is vital for the immune system. It can activate the white blood cells and enhance the ability of them to emulsify bacteria. While viruses and bacteria are evolving and numerous new diseases emerged, further protection for children and elderly are required. Studies also show that vitamin C is necessary in reducing duration of cold and flu symptoms.\u003cbr\u003eVitamin C has important role in the formation of collagen which is essential in healing process. It also promotes iron movement and absorption, enhances folic acid and body metabolism. Vitamin C is an antioxidant which neutralizes free radicals and prevents oxidative damage. This effect can help to prevent wrinkles and other health problems.\u003c\/p\u003e\n\u003ch4\u003eVitamin D for Calcium Absorption\u003c\/h4\u003e\n\u003cp\u003eVitamin D is an essential nutrient that contributes to healthy, strong bones and regulates the amount of calcium in the body. Vitamin D can be synthesized by our skin through sunlight exposure or absorbed from normal diet. However, less than 10% of the diet contain adequate amount of Vitamin D. People who spend most of the time indoor or elderly who have mobility problem are less likely exposed to sunlight and thus they are at risk of vitamin D deficiency and require supplementary intake.\u003cbr\u003eVitamin D promotes calcium absorption in the gut and maintains adequate calcium level which can enhance bone growth and teeth health. Vitamin D deficiency reduces calcium and phosphorus absorption and can lead to poor mineralization in the bones or even other health issues.\u003c\/p\u003e","brand":"YesNutri \/ Smart Children’s Supplements","offers":[{"title":"No outer boxes","offer_id":47299649274007,"sku":null,"price":268.0,"currency_code":"HKD","in_stock":true},{"title":"Require outer box (it will be provided if available)","offer_id":47299649306775,"sku":null,"price":268.0,"currency_code":"HKD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0721\/2980\/6487\/files\/YesNutri_SC0010_Kids_Growth_Calcium_Chewable_Tablets_main400x400.jpg?v=1773444937"},{"product_id":"yesnutri-glucosamine-chondroitin-joints-cream","title":"YesNutri Glucosamine – Chondroitin Joints Cream","description":"\u003cdiv class=\"ds-virtual-list-items _6f2c522\"\u003e\n\u003cdiv class=\"ds-virtual-list-visible-items\"\u003e\n\u003cdiv data-virtual-list-item-key=\"38\" class=\"_4f9bf79 d7dc56a8 _43c05b5\"\u003e\n\u003cdiv class=\"ds-message _63c77b1\"\u003e\n\u003cdiv class=\"ds-markdown ds-assistant-message-main-content\"\u003e\n\u003cul\u003e\n\u003cli class=\"ds-markdown-paragraph\"\u003e\u003cspan class=\"\"\u003eImprove joint mobility\u003c\/span\u003e\u003c\/li\u003e\n\u003cli class=\"ds-markdown-paragraph\"\u003e\u003cspan class=\"\"\u003eMaintain bone and joint health\u003c\/span\u003e\u003c\/li\u003e\n\u003cli class=\"ds-markdown-paragraph\"\u003e\u003cspan class=\"\"\u003eEnhance cartilage regeneration\u003c\/span\u003e\u003c\/li\u003e\n\u003cli class=\"ds-markdown-paragraph\"\u003e\u003cspan class=\"\"\u003eRelieve joint pain and weakness\u003c\/span\u003e\u003c\/li\u003e\n\u003cli class=\"ds-markdown-paragraph\"\u003e\u003cspan class=\"\"\u003eStrengthen muscle and joints\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003ch3\u003eProduct Introduction\u003c\/h3\u003e\n\u003cp\u003eYesNutri Glucosamine Chondroitin Joints Cream provides protection for people who suffer from joint problems, including fatigue, obesity, lack of exercise, intensive cell phone users and elderly. The four high quality elements, including glucosamine, chondroitin, collagen and MSM, work together to repair and supplement cartilage tissues. Gently massage to let the ingredients penetrate and target the sore and pain. It can be applied to wrist, fingers, knee, waist, back, neck and other positions. This formula is a good alternative other than medicines.\u003c\/p\u003e\n\u003ch3\u003eProduct Name\u003c\/h3\u003e\n\u003cp\u003eYesNutri Glucosamine – Chondroitin Joints Cream (Tube)\u003c\/p\u003e\n\u003ch3\u003ePack Size\u003c\/h3\u003e\n\u003cp\u003e30G\/ 50G \/4 Oz (113.4g)\u003c\/p\u003e\n\u003ch3\u003ePlace of Origin\u003c\/h3\u003e\n\u003cp\u003eAmerica\u003c\/p\u003e\n\u003ch3\u003eComposition\u003c\/h3\u003e\n\u003cp\u003ePurified water, paraffinum liquidum, stearic acid, hexadecanol, menthol, sorbitol, cyclomethicone, triethanolamine, MSM, Glucosamine Sulfate, Chondroitin, Collagen Hydrolysate, sodium chloride, EDTA, methylchloroisothiazolinone, and methylisothiazolinone.\u003c\/p\u003e\n\u003ch3\u003eDirection\u003c\/h3\u003e\n\u003cp\u003eApply three times a day. Gently massage until the cream has been absorbed into your skin.\u003c\/p\u003e\n\u003ch3\u003eDescription\u003c\/h3\u003e\n\u003cp\u003eActive Ingredients offer multiple benefits\u003c\/p\u003e\n\u003ch4\u003eGlucosamine\u003c\/h4\u003e\n\u003cp\u003e1. Important construction material for cartilage and connective tissues\u003cbr\u003e2. Maintain water content in joints\u003cbr\u003e3. Create flexible joints\u003cbr\u003e4. Relieve joint pain\u003c\/p\u003e\n\u003ch4\u003eChondroitin\u003c\/h4\u003e\n\u003cp\u003e1. Lock water inside cartilage tissue\u003cbr\u003e2. Avoid cartilage breakdown\u003cbr\u003e3. Provide material for cartilage reconstruction\u003cbr\u003e4. Resist pressure from locomotion and weight\u003c\/p\u003e\n\u003ch4\u003eCollagen\u003c\/h4\u003e\n\u003cp\u003e1. Forming part of the muscle and tendon\u003cbr\u003e2. Maintain cartilage elasticity and joint flexibility\u003cbr\u003e3. Strengthen muscle and joint\u003c\/p\u003e\n\u003ch4\u003eMethylsulfonylmethane (MSM)\u003c\/h4\u003e\n\u003cp\u003e1. Help in formation of new cells\u003cbr\u003e2. Rebuild cartilage tissues\u003cbr\u003e3. Optimum to be used with the other three ingredients\u003c\/p\u003e","brand":"YesNutri \/ Specialized Needs","offers":[{"title":"113g(4Oz)","offer_id":47323902836887,"sku":null,"price":128.0,"currency_code":"HKD","in_stock":true},{"title":"30g","offer_id":47323902869655,"sku":null,"price":48.0,"currency_code":"HKD","in_stock":false},{"title":"50g","offer_id":47323902902423,"sku":null,"price":68.0,"currency_code":"HKD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0721\/2980\/6487\/files\/SN002B_Glucosamine_Chondroitin_Joints_Cream_Tube_30gmain-1-scaled.jpg?v=1773511801"},{"product_id":"yesnutri-glucosamine-4-in-1-joint-formula","title":"YesNutri Glucosamine 4 in 1 Joint Formula","description":"\u003cul\u003e\n\u003cli\u003e\u003cspan class=\"\"\u003eImprove joint mobility, enhance cartilage recovery\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan class=\"\"\u003eRelieve joint pain\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan class=\"\"\u003eStrengthen muscles and joints\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan class=\"\"\u003eMaintain normal bone density\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan class=\"\"\u003eBoost calcium absorption\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eProduct Introduction\u003c\/h3\u003e\n\u003cp\u003eYesNutri Glucosamine 4 in 1 Joint Formula not only provides glucosamine and chondroitin, but also calcium and vitamin D. Nowadays, working class does not expose to enough sunlight, making them at risk of inadequate vitamin D due to the low level of synthesis. This formula not only helps repair joints, it also provides supplementation of structural components for the skeleton. Glucosamine is the key component of joints and cartilages. It works with chondroitin to lock water content in cartilage, keeping the joint flexible and relieving pain.\u003c\/p\u003e\n\u003ch3\u003eProduct Name\u003c\/h3\u003e\n\u003cp\u003eYesNutri Glucosamine 4 in 1 Joint Formula\u003c\/p\u003e\n\u003ch3\u003ePack Size\u003c\/h3\u003e\n\u003cp\u003e30\/ 60\/ 300 Tablets\u003c\/p\u003e\n\u003ch3\u003ePlace of Origin\u003c\/h3\u003e\n\u003cp\u003eU.S.A.\u003c\/p\u003e\n\u003ch3\u003eComposition\u003c\/h3\u003e\n\u003cp\u003eEach tablet contains:\u003c\/p\u003e\n\u003cp\u003eGlucosamine Sulfate 2KCL 1500mg\u003cbr\u003eChondroitin Sulfate Sodium 500mg\u003cbr\u003eCalcium Carbonate 120mg (including 40 mg of calcium)\u003cbr\u003eVitamin D 200IU\u003c\/p\u003e\n\u003ch3\u003eDirection\u003c\/h3\u003e\n\u003cp\u003eAdults take 1 tablet daily preferably with a meal or as recommended by a physician.\u003c\/p\u003e\n\u003ch3\u003eDescription\u003c\/h3\u003e\n\u003ch4\u003eGlucosamine \u0026amp; Chondroitin Help Rebuild Cartilage\u003c\/h4\u003e\n\u003cp\u003eGlucosamine is an amino sugar which exists in our body in form of proteoglycans. Proteoglycan is found in articular cartilage and other connective tissues. Its viscoelastic property keeps large amount of water in cartilage, and makes glucosamine a key component of articular cartilage. Deficiency symptoms of glucosamine may include joint swelling, soreness, hip discomfort, degeneration of spinal column, vertebral bone and knee canopy.\u003c\/p\u003e\n\u003cp\u003eChondroitin is an important structural component of cartilage and provides much of its resistance to compression. It is a complex carbohydrate that helps cartilage to retain water. It may also block enzymes that break down cartilage, and provide building blocks for the body to produce new cartilage.\u003c\/p\u003e\n\u003ch4\u003eCalcium and Vitamin D3 to Maintain Strong Bones\u003c\/h4\u003e\n\u003cp\u003eOur bones have significant physical functions like support, protection and exercise. It also acts as storage and reservoir for calcium. When the body is deficient of calcium, our bones and teeth will become fragile, and we can neither maintain normal heartbeat, nor control body movement and metabolism. In aging adults, particularly among postmenopausal women, bone breakdown exceeds formation, resulting in bone loss that increases the risk of bone fracture over time.\u003c\/p\u003e\n\u003cp\u003eVitamin D3, also known as cholecalciferol, is a fat soluble vitamin which facilitates body absorption of calcium. Vitamin D3 helps promote intestinal calcium absorption, enhance bone growth and calcification, and keep our teeth strong. Although we can obtain vitamin D3 through diet and sunlight, people nowadays mostly work indoor and thus are at risk of insufficient vitamin D3. It is essential to take dietary supplement for adequate vitamin D3 intake and as such to maintain calcium concentration.\u003c\/p\u003e","brand":"YesNutri \/ Specialized Needs","offers":[{"title":"30-tablets \/ No outer boxes","offer_id":47344606183575,"sku":null,"price":358.0,"currency_code":"HKD","in_stock":true},{"title":"30-tablets \/ Require outer box (it will be provided if available)","offer_id":47344606216343,"sku":null,"price":358.0,"currency_code":"HKD","in_stock":true},{"title":"60-tablets \/ No outer boxes","offer_id":47344606249111,"sku":null,"price":578.0,"currency_code":"HKD","in_stock":true},{"title":"60-tablets \/ Require outer box (it will be provided if available)","offer_id":47344606281879,"sku":null,"price":578.0,"currency_code":"HKD","in_stock":true},{"title":"300-tablets \/ No outer boxes","offer_id":47344606314647,"sku":null,"price":2288.0,"currency_code":"HKD","in_stock":true},{"title":"300-tablets \/ Require outer box (it will be provided if available)","offer_id":47344606347415,"sku":null,"price":2288.0,"currency_code":"HKD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0721\/2980\/6487\/files\/YesNutri_SN004_Glucosamine_4in1_30s_main2-scaled.jpg?v=1773599749"},{"product_id":"yesnutri-herbal-cool-patch","title":"YesNutri Herbal Cool-Patch","description":"\u003cul\u003e\n\u003cli\u003e\u003cspan class=\"\"\u003eEffectively relieve discomfort of muscle fatigue and pain\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan class=\"\"\u003eRelieve stiff shoulder\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan class=\"\"\u003eRelieve sprains, strains and mild backache.\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eProduct Introduction\u003c\/h3\u003e\n\u003cp\u003eYesNutri Herbal Cool-Patch can effectively relieve discomfort of muscle fatigue and pain, stiff shoulder, knee and elbow pain, bruises, sprains, strains, mild backache and lumbago. It is suitable for people who suffer from fatigue or feel muscle tension after exercise.\u003c\/p\u003e\n\u003ch3\u003eProduct Name\u003c\/h3\u003e\n\u003cp\u003eYesNutri Herbal Cool-Patch\u003c\/p\u003e\n\u003ch3\u003ePack Size\u003c\/h3\u003e\n\u003cp\u003e5 \/ 10 \/ 60 Patches\u003c\/p\u003e\n\u003ch3\u003ePlace of Origin\u003c\/h3\u003e\n\u003cp\u003eTaiwan\u003c\/p\u003e\n\u003ch3\u003eComposition\u003c\/h3\u003e\n\u003cp\u003eEach patch contains:\u003cbr\u003eTuomailin, Rhus Javanica Leaf Extract, Murraya Paniculata Leaf Extract, Tea Tree Oil, Mint Leaf Extract, Natural Resin, Flemingiae Lineatae Radix.\u003c\/p\u003e\n\u003ch3\u003eDirection\u003c\/h3\u003e\n\u003cp\u003eAdults and children aged 12 and above: apply to affected area once or twice a day. Remove after 8 hours.\u003c\/p\u003e\n\u003ch3\u003eDescription\u003c\/h3\u003e\n\u003cp\u003eStop using this product and consult your doctor if:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eConditions worsen, persistence of symptoms\u003c\/li\u003e\n\u003cli\u003eRash, itching or excessive skin irritation occurs\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"YesNutri \/ Specialized Needs","offers":[{"title":"5-patches \/ No outer boxes","offer_id":47344747970711,"sku":null,"price":68.0,"currency_code":"HKD","in_stock":true},{"title":"5-patches \/ Require outer box (it will be provided if available)","offer_id":47344748003479,"sku":null,"price":6800768.0,"currency_code":"HKD","in_stock":true},{"title":"10-patches \/ No outer boxes","offer_id":47344748036247,"sku":null,"price":108.0,"currency_code":"HKD","in_stock":true},{"title":"10-patches \/ Require outer box (it will be provided if available)","offer_id":47344748069015,"sku":null,"price":108.0,"currency_code":"HKD","in_stock":true},{"title":"60-patches \/ No outer boxes","offer_id":47344748101783,"sku":null,"price":768.0,"currency_code":"HKD","in_stock":true},{"title":"60-patches \/ Require outer box (it will be provided if available)","offer_id":47344748134551,"sku":null,"price":6800768.0,"currency_code":"HKD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0721\/2980\/6487\/files\/Yesnutri_-5__new_pack-scaled_1.jpg?v=1773604356"},{"product_id":"yesnutri-herbal-warm-patch","title":"YesNutri Herbal Warm-Patch","description":"\u003cdiv class=\"ds-virtual-list-items _6f2c522\"\u003e\n\u003cdiv class=\"ds-virtual-list-visible-items\"\u003e\n\u003cdiv class=\"_4f9bf79 d7dc56a8 _43c05b5\" data-virtual-list-item-key=\"30\"\u003e\n\u003cdiv class=\"ds-message _63c77b1\"\u003e\n\u003cdiv class=\"ds-markdown ds-assistant-message-main-content\"\u003e\n\u003cul\u003e\n\u003cli class=\"ds-markdown-paragraph\"\u003e\u003cspan class=\"\"\u003eEffectively relieve discomfort of muscle fatigue and pain\u003c\/span\u003e\u003c\/li\u003e\n\u003cli class=\"ds-markdown-paragraph\"\u003e\u003cspan class=\"\"\u003eRelieve stiff shoulder\u003c\/span\u003e\u003c\/li\u003e\n\u003cli class=\"ds-markdown-paragraph\"\u003e\u003cspan class=\"\"\u003eRelieve sprains, strains and mild backache.\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003ch3\u003eProduct Introduction\u003c\/h3\u003e\n\u003cp\u003eYesNutri Herbal Warm-Patch contains a variety of herbal extracts, providing a warm sensation with strong penetration. It can be used for joints, lower back, shoulders, neck, hands, feet, knees, elbows, etc., helping to regulate meridian, remove dampness, and release tension.\u003c\/p\u003e\n\u003ch3\u003eProduct Name\u003c\/h3\u003e\n\u003cp\u003eYesNutri Herbal Warm-Patch (Addition of Tuomailin)\u003c\/p\u003e\n\u003ch3\u003ePack Size\u003c\/h3\u003e\n\u003cp\u003e5 Patches\u003c\/p\u003e\n\u003ch3\u003ePlace of Origin\u003c\/h3\u003e\n\u003cp\u003eTaiwan\u003c\/p\u003e\n\u003ch3\u003eComposition\u003c\/h3\u003e\n\u003cp\u003eEach patch contains:\u003c\/p\u003e\n\u003cp\u003eTuomailin, Natural Resin, Glycine tomentella Hayata Extract, Rhus Javanica Leaf Extract, Cymbopogon citratus Oil, Mint Leaf Extract, Capsicum annuum Extract\u003c\/p\u003e\n\u003ch3\u003eDirection\u003c\/h3\u003e\n\u003cp\u003eAdults and children aged 12 and above: apply to affected area once or twice a day. Remove after 8 hours.\u003c\/p\u003e\n\u003ch3\u003eDescription\u003c\/h3\u003e\n\u003cp\u003eStop using this product and consult your doctor if:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eConditions worsen, persistence of symptoms\u003c\/li\u003e\n\u003cli\u003eRash, itching or excessive skin irritation occurs\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eFOR EXTERNAL USE ONLY\u003c\/p\u003e","brand":"YesNutri \/ Specialized Needs","offers":[{"title":"Default Title","offer_id":47344979017879,"sku":null,"price":68.0,"currency_code":"HKD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0721\/2980\/6487\/files\/SN054_Herbal-Warm-Patch__front.jpg?v=1773613583"},{"product_id":"yesnutri-joint-care-gold-tablets","title":"YesNutri Joint Care Gold Tablets","description":"\u003cul\u003e\n\u003cli\u003e\u003cspan class=\"\"\u003eAssists bone remodeling\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan class=\"\"\u003eHelps relieve joint pain and swelling\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan class=\"\"\u003eRepairing bones and worn-out joints and soft tissues\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan class=\"\"\u003eLubricate joints\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan class=\"\"\u003eEnhance joint mobility\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan class=\"\"\u003eRelieve the pain caused by chronic arthritis\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan class=\"\"\u003eEnhance bone strength\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan class=\"\"\u003eReduce bone loss\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan class=\"\"\u003eEnhance the absorption of calcium.\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eProduct Introduction\u003c\/h3\u003e\n\u003cp\u003eYesNutri Joint Care Gold Tablet is an outstanding product combining high quality Collagen, Pharma Grade Chondroitin, with MSM and Herbs. This product is manufactured by a well-known USA cGMP manufacturer.\u003c\/p\u003e\n\u003ch4\u003eAn all-rounded Supplement\u003c\/h4\u003e\n\u003cp\u003eJoint Care Gold Tablets (11 in 1 Formula) is a high graded product made from 11 kinds of high quality Collagen, Glucosamine, Chondroitin, with MSM and Herbal Extracts. It assists bone remodeling, helps relieve joint pain and swelling, enhance joint mobility and lubricate joints. Besides, this product contain vitamin C can enhance collagen production for repairing bones and worn-out joints and soft tissues. Vitamin D3 can enhance the absorption of minerals such as calcium and phosphorus, enhance bone strength and reduce bone loss. Vitamin C and D3 both enhance the immune system.\u003c\/p\u003e\n\u003ch3\u003eComposition\u003c\/h3\u003e\n\u003cp\u003eGlucosamine hydrochloride, chondroitin sulfate, collagen hydrolysate, emulsifier (460,462), MSM (methyl sulfonyl methane), boswellia serrata extract, turmeric extract, anticaking agent (551,570,572), ascorbic acid, sodium borate , stabilizer (468), glazing agent (904), manganese sulfate, cholecalciferol, nattokinase\u003c\/p\u003e\n\u003ch3\u003eDirections\u003c\/h3\u003e\n\u003cp\u003eAdult: Take 1 tablet 2 times daily.\u003c\/p\u003e\n\u003ch3\u003eStorage\u003c\/h3\u003e\n\u003cp\u003eStore below 25℃ in a dry and cool place.\u003c\/p\u003e\n\u003cp\u003eKeep out of reach of children.\u003c\/p\u003e\n\u003ch3\u003eJoint Care Gold Tablet\u003c\/h3\u003e\n\u003ch4\u003eImportance of Collagen Supplementation\u003c\/h4\u003e\n\u003cp\u003eStarting from the age of 25, our collagen level reduces at a rate of 1.5% every year as part of the aging process. Collagen reduction will increase the risk of suffering joints pain and elongate the recovery time from injury. And by the age of 45, collagen level in our body will reduce by up to 30%.\u003csup\u003e1,2\u003c\/sup\u003e\u003c\/p\u003e\n\u003ch4\u003eAttributes of the Joint Nourishing Ingredients\u003c\/h4\u003e\n\u003cp\u003eCollagen is the main structural protein found in our body. It accounts for about 30% of all protein in our body and is essential for the growth and development of muscles, tendons and bones. Collagen also provides the strength and elasticity that our body tissues need.\u003csup\u003e3-5\u003c\/sup\u003e Studies have shown that collagen hydrolysate can effectively replace the collagen that is lost through normal aging process.\u003csup\u003e7,8\u003c\/sup\u003e Not only is this beneficial to our muscles and joints, it can also help to keep our skin, hair and nails healthy.\u003csup\u003e7,8\u003c\/sup\u003e\u003c\/p\u003e\n\u003cp\u003eChondroitin Sulphate comes from natural resource, such as shark or bovine cartilage.\u003csup\u003e9-11\u003c\/sup\u003e It is a major component of cartilage – the tough, connective tissue that cushions the joints.\u003csup\u003e9-11\u003c\/sup\u003e Chondroitin helps to keep cartilage healthy by absorbing fluid (particularly water) into the connective tissue.\u003csup\u003e9-11\u003c\/sup\u003e It may also block enzymes that break down cartilage, and provide the building blocks for the body to produce new cartilage.\u003csup\u003e9-11\u003c\/sup\u003e\u003c\/p\u003e\n\u003cp\u003eGlucosamine plays an important role in making glycosaminoglycans and glycoproteins, which are essential building blocks of many parts of your joints, including ligaments, tendons, cartilage and synovial fluid.\u003csup\u003e20\u003c\/sup\u003e\u003c\/p\u003e\n\u003cp\u003eMSM (Methylsulfonylmethane) is an important source of organic sulfur, which is required for development and maintenance of connective tissues.\u003csup\u003e13-15\u003c\/sup\u003e MSM can strengthen and increase flexibility of the muscles, bones and joints. MSM is also the vital component in the formation of keratin, collagen and elastin, which smooths the skin, strengthens hair and nails and enhance growth of hair and nails.\u003csup\u003e13-17\u003c\/sup\u003e\u003c\/p\u003e\n\u003cp\u003eManganese and Boron are essential trace mineral elements for the body, especially for bones and muscles. Manganese helps increase bone density and prevents bone loss.\u003csup\u003e22\u003c\/sup\u003e Boron focuses on bone health and muscle. It aid for building muscles and for improving muscle coordination to support joint activities.\u003csup\u003e23,24\u003c\/sup\u003e\u003c\/p\u003e\n\u003ch4\u003eAttributes of the Relieving Joint Discomfort Ingredients\u003c\/h4\u003e\n\u003cp\u003eBoswellia is an Indian herb. Its natural extract comes from the gums and resins of Boswellia serrata.\u003csup\u003e12,13\u003c\/sup\u003e Boswellia helps to remove toxin from the joints, support and increase the mobility of the joints, suppress underlying pain, reduce joint swells and stiffness.\u003csup\u003e12,13\u003c\/sup\u003e\u003c\/p\u003e\n\u003cp\u003eTurmeric can extract a yellow coloring agent named curcumin. It shows strong anti-oxidative and anti-inflammatory activities.\u003csup\u003e27\u003c\/sup\u003e It can play a key role in the prevention of chronic inflammation diseases as it able to reduce the oxidative stress of the body; Curcumin can relieve the pain caused by chronic arthritis.\u003csup\u003e28\u003c\/sup\u003e\u003c\/p\u003e\n\u003cp\u003eNattokinase is an enzyme that is extracted from a popular Japanese food called natto, which is boiled soybeans that have been fermented with a bacterium called Bacillus subtilis natto.\u003csup\u003e25\u003c\/sup\u003e Nattokinase has the ability of dissolving fibrin and acts as an anticoagulant. It may reduce blood clot and enhance blood flow to supply the nutrients for bone, joint and cartilage tissue repairing or reconstruction.\u003csup\u003e26,28\u003c\/sup\u003e\u003c\/p\u003e\n\u003ch4\u003eAdvance Technology in Hydrolyzed Collagen Production\u003c\/h4\u003e\n\u003cp\u003eBy means of advance technology, the fine product resulting from bone and cartilage that has been broken down into small components that can collectively be referred to as hydrolyzed collagen. Hydrolyzed collagen can easily be absorbed throughout the body and rejuvenate our bones, joints and cartilage.\u003c\/p\u003e\n\u003ch4\u003eAn all-rounded Supplement\u003c\/h4\u003e\n\u003cp\u003eCollagen Hydrolysate (Enriched with Glucosamine, Chondroitin, MSM and Herbal Extracts) is a high graded product made from 11 kinds of high quality Collagen, Glucosamine, Chondroitin, with MSM and Herbal Extracts. It assists bone remodeling, helps relieve joint pain and swelling, enhance joint mobility and lubricate joints. Besides, this product contain vitamin C can enhance collagen production for repairing bones and worn-out joints and soft tissues. Vitamin D3 can enhance the absorption of minerals such as calcium and phosphorus, enhance bone strength and reduce bone loss. Vitamin C and D3 both enhance the immune system.\u003c\/p\u003e\n\u003ch4\u003eBeneficial effects of Collagen Hydrolysate Plus MSM include:\u003c\/h4\u003e\n\u003cul\u003e\n\u003cli\u003ereduce risk of joint pain and swelling\u003csup\u003e7,10-17,21,23,24,28\u003c\/sup\u003e\n\u003c\/li\u003e\n\u003cli\u003epromote cartilage formation in joints\u003csup\u003e7,10-17\u003c\/sup\u003e\n\u003c\/li\u003e\n\u003cli\u003emaintain healthy cartilage and supplement synovial fluid\u003csup\u003e7,10-17\u003c\/sup\u003e\n\u003c\/li\u003e\n\u003cli\u003ehelp regulate skin tone, firmness and reduce cellulite\u003csup\u003e6,18\u003c\/sup\u003e\n\u003c\/li\u003e\n\u003cli\u003eanti-oxidizing effect\u003csup\u003e21,24\u003c\/sup\u003e\n\u003c\/li\u003e\n\u003cli\u003ereduce fine lines, wrinkles, stretch marks and scars\u003csup\u003e19\u003c\/sup\u003e\n\u003c\/li\u003e\n\u003cli\u003esmooths the skin, strengthen hair and nails\u003csup\u003e13-15\u003c\/sup\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch4\u003eRecommended daily dose:\u003c\/h4\u003e\n\u003cp\u003eAdults take 1 tablet twice daily, or as directed by physicians.\u003c\/p\u003e\n\u003ch4\u003eReferences\u003c\/h4\u003e\n\u003col\u003e\n\u003cli\u003eHall DA. The pathophysiology of ageing collagen. Proc R Soc Med. 1976;69(12): 923-4.\u003c\/li\u003e\n\u003cli\u003eMoriguchi T, Fujimoto D. Age-related changes in the content of the collagen crosslink, pyridinoline. J Biochem. 1978;84(4):933-5.\u003c\/li\u003e\n\u003cli\u003eDi Lullo GA, Sweeney SM, Korkko J, Ala-Kokko L, San Antonio JD. Mapping the ligand-binding sites and disease-associated mutations on the most abundant protein in the human, type I collagen. J Biol Chem. 2002;277(6):4223-31.\u003c\/li\u003e\n\u003cli\u003eLodish H, Berk A, Zipursky SL, Matsudaira P, Baltimore D, Darnell J. Collagen: The Fibrous Proteins of the Matrix. Molecular Cell Biology (4th ed). New York: W. H. Freeman; 2000.\u003c\/li\u003e\n\u003cli\u003eBailey AJ, Paul RG, Knott L. Mechanisms of maturation and ageing of collagen. Mech Ageing Dev. 1998;106(1-2):1-56.\u003c\/li\u003e\n\u003cli\u003eBaumann L. Skin ageing and its treatment. J Pathol. 2007;211(2):241-51.\u003c\/li\u003e\n\u003cli\u003eZague V, de Freitas V, da Costa Rosa M, de Castro GÁ, Jaeger RG, Machado-Santelli GM. Collagen hydrolysate intake increases skin collagen expression and suppresses matrix metalloproteinase 2 activity. J Med Food. 2011;14(6):618-24.\u003c\/li\u003e\n\u003cli\u003eLiang J, Pei X, Zhang Z, Wang N, Wang J, Li Y. The protective effects of long-term oral administration of marine collagen hydrolysate from chum salmon on collagen matrix homeostasis in the chronological aged skin of Sprague-Dawley male rats. J Food Sci. 2010;75(8):H230-8.\u003c\/li\u003e\n\u003cli\u003eChai HJ, Li JH, Huang HN, Li TL, Chan YL, Shiau CY, Wu CJ. Effects of sizes and conformations of fish-scale collagen peptides on facial skin qualities and transdermal penetration efficiency. J Biomed Biotechnol. 2010 June 8, doi: 10.1155\/2010\/757301.\u003c\/li\u003e\n\u003cli\u003eMONOGRAPHS Chondroitin Sulfates. Altern Med Rev. 2006;10(4):338-43.\u003c\/li\u003e\n\u003cli\u003eGregory PJ, Sperry M, Wilson AF. Dietary supplements for osteoarthritis. Am Fam Physician. 2008; 77(2): 177-84.\u003c\/li\u003e\n\u003cli\u003eGupta PK, Samarakoon SM, Chandola HM, Ravishankar B. Clinical evaluation of Boswellia serrata (Shallaki) resin in the management of Sandhivata (osteoarthritis). Ayu. 2011;32(4):478-82.\u003c\/li\u003e\n\u003cli\u003eWe SR, Jeong EO, Koog YH, Min BI. Effects of nutraceuticals on knee osteoarthritis: Systematic review. Afr J Biotechnol. 2012;11(12):2814-21.\u003c\/li\u003e\n\u003cli\u003eMONOGRAPHS Methylsulfonylmethane (MSM). Altern Med Rev. 2003;8(4):438-41.\u003c\/li\u003e\n\u003cli\u003eRoth RA, Townsend CE. Sulfur (MSM) – A Basic Essential Nutrient Needed Now, More than Ever Before. Nutrition \u0026amp; Diet Therapy (8th ed). New York: Academic Press; 2003.\u003c\/li\u003e\n\u003cli\u003eDebbi EM, Agar G, Fichman G, Ziv YB, Kardosh R et al.Efficacy of methylsulfonylmethane supplementation on osteoarthritis of the knee: a randomized controlled study. BMC Complement Altern Med. 2011;11:50.\u003c\/li\u003e\n\u003cli\u003eMagrans-Courtney T, Wilborn C, Rasmussen C, Ferreira M, Greenwood L et al. Effects of diet type and supplementation of glucosamine, chondroitin, and MSM on body composition, functional status, and markers of health in women with knee osteoarthritis initiating a resistance-based exercise and weight loss program. J Int Soc Sports Nutr. 2011;8:8.\u003c\/li\u003e\n\u003cli\u003eRawlings AV. Cellulite and its treatment. Int J Cosmet Sci. 2006;28(3):175-90.\u003c\/li\u003e\n\u003cli\u003eBauza E, Oberto G, Berghi A, Dal CF, Domloge N. Collagen-like peptide exhibits a remarkable antiwrinkle effect on the skin when topically applied: in vivo study. Int J Tissue React. 2004;26(3-4):105-11.\u003c\/li\u003e\n\u003cli\u003eThoria Donia, Ehab M.M. Ali, Abdel-Halim Abdel-Hady Mostafa. Biochemical Effects of glucosamine on glycoproteins of rats with hepatic fibrosis. Int. J. of Adv. Res. 2016;4(3): 1845-1859] (ISSN 2320-5407).\u003c\/li\u003e\n\u003cli\u003eHe Y, Yue Y, Zheng X, Zhang K, Chen S, Du Z. Curcumin, inflammation, and chronic diseases: how are they linked? Molecules. 2015 May 20;20(5):9183-213. doi: 10.3390\/molecules20059183. PMID: 26007179; PMCID: PMC6272784.\u003c\/li\u003e\n\u003cli\u003eKeen CL, Zidenberg-Cherr S. Manganese. In: Ziegler EE, Filer LJ, eds. Present Knowledge in Nutrition. 7th ed. Washington D.C.: ILSI Press; 1996:334-343.\u003c\/li\u003e\n\u003cli\u003eNewnham RE. Essentiality of boron for healthy bones and joints. Environ Health Perspect. 1994 Nov; 102 Suppl 7(Suppl 7):83-5. doi: 10.1289\/ehp.94102s783. PMID: 7889887; PMCID: PMC1566627.\u003c\/li\u003e\n\u003cli\u003eNielsen FH. Biochemical and physiologic consequences of boron deprivation in humans. Environ Health Perspect. 1994;102(suppl 7):59–63.\u003c\/li\u003e\n\u003cli\u003eYanagisawa Y, Chatake T, Chiba-Kamoshida K, Naito S, Ohsugi T, Sumi H, et al. (December 2010). \"Purification, crystallization and preliminary X-ray diffraction experiment of nattokinase from Bacillus subtilis natto\". Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 66 (Pt 12): 1670–3. doi:10.1107\/S1744309110043137. PMC 2998380. PMID 21139221.\u003c\/li\u003e\n\u003cli\u003eKurosawa Y, Nirengi S, Homma T, et al. A single-dose of oral nattokinase potentiates thrombolysis and anti-coagulation profiles. Sci Rep. 2015;5:11601. Published 2015 Jun 25. doi:10.1038\/srep11601.\u003c\/li\u003e\n\u003cli\u003eNational Center for Biotechnology Information. PubChem Compound Summary for CID 969516, Curcumin. https:\/\/pubchem.ncbi.nlm.nih.gov\/compound\/Curcumin. Accessed Dec. 11, 2020.\u003c\/li\u003e\n\u003cli\u003eChaiyasit, Kamon, and Viroj Wiwanitkit. \"Natto supplementation and decreased platelet count in a case with rheumatoid arthritis.\" Annals of Tropical Medicine and Public Health, vol. 6, no. 3, 2013, p. 387. Accessed 11 Dec. 2020.\u003c\/li\u003e\n\u003c\/ol\u003e","brand":"YesNutri \/ Specialized Needs","offers":[{"title":"30-tablets \/ No outer boxes","offer_id":47349930786967,"sku":null,"price":358.0,"currency_code":"HKD","in_stock":true},{"title":"30-tablets \/ Require outer box (it will be provided if available)","offer_id":47349930819735,"sku":null,"price":358.0,"currency_code":"HKD","in_stock":true},{"title":"60-tablets \/ No outer boxes","offer_id":47349930852503,"sku":null,"price":578.0,"currency_code":"HKD","in_stock":true},{"title":"60-tablets \/ Require outer box (it will be provided if available)","offer_id":47349930885271,"sku":null,"price":578.0,"currency_code":"HKD","in_stock":true},{"title":"200-tablets \/ No outer boxes","offer_id":47349930918039,"sku":null,"price":1610.0,"currency_code":"HKD","in_stock":true},{"title":"200-tablets \/ Require outer box (it will be provided if available)","offer_id":47349930950807,"sku":null,"price":1610.0,"currency_code":"HKD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0721\/2980\/6487\/files\/YesNutri_SN038_Joint-Care_30s_main-1.jpg?v=1773667302"},{"product_id":"卓營方-supra-nmn-30000","title":"YesNutri Supra NMN 30000+","description":"\u003cul\u003e\n\u003cli\u003e\u003cspan class=\"\"\u003eRestores youthful function\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan class=\"\"\u003eActs as an effective antioxidant for eye protection\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan class=\"\"\u003eImproves skin condition\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan class=\"\"\u003eStrengthens cardiac function\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan class=\"\"\u003eEnhances brain capabilities\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003eProduct Introduction\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eYesNutri Supra NMN 30000+ contains five upgraded ingredients – NMN, coenzyme Q10, PQQ, resveratrol, and astaxanthin. Each capsule contains 500 mg of NMN with a purity of 99.9%. Combined with the other four highly effective antioxidant components, it helps you maintain youthfulness, keep unlimited vitality, and achieve the optimal anti-aging effect.\u003c\/p\u003e\n\u003cp\u003eNMN – Activates cellular functions, slows down aging, and enhances the body's repairability.\u003c\/p\u003e\n\u003cp\u003eAstaxanthin – Maintains eye health and delays visual aging.\u003c\/p\u003e\n\u003cp\u003eResveratrol – Highly moisturizing, enhances skin elasticity, and maintains a youthful appearance.\u003c\/p\u003e\n\u003cp\u003ePQQ – Activates brain cells to have more energy, making the brain more agile and clear, and enhancing memory.\u003cbr\u003eCoenzyme Q10 – Promotes cellular energy conversion and metabolism, strengthen heart function\u003c\/p\u003e\n\u003ch3\u003eProduct Name\u003c\/h3\u003e\n\u003cp\u003eYesNutri Supra NMN 30000+\u003c\/p\u003e\n\u003ch3\u003ePack Size\u003c\/h3\u003e\n\u003cp\u003e60 Veggie Capsules\u003c\/p\u003e\n\u003ch3\u003ePlace of Origin\u003c\/h3\u003e\n\u003cp\u003eAmerica\u003c\/p\u003e\n\u003ch3\u003eComposition\u003c\/h3\u003e\n\u003cp\u003eper capsule\u003c\/p\u003e\n\u003cp\u003eBeta-nicotinamide mononucleotide(NMN) 500mg\u003cbr\u003eCoenzyme Q10 30mg\u003cbr\u003eReseveratrol 20mg\u003cbr\u003ePyrroloquinoliine Quinone(PQQ) 20mg\u003cbr\u003eAstaxanthin 2mg\u003cbr\u003eCanthaxanthin 36mcg\u003cbr\u003eBeta-carotene 32mcg\u003cbr\u003eLutein 20mcg\u003c\/p\u003e\n\u003ch3\u003eDirections\u003c\/h3\u003e\n\u003cp\u003eFirst using: take 1 capsule dailt in the first month continuously.\u003c\/p\u003e\n\u003cp\u003eAdcanced care: take 1-2 capsules daily or as directed by physicians.\u003c\/p\u003e\n\u003ch3\u003eStorage\u003c\/h3\u003e\n\u003cp\u003eStore below 25 degrees in a dry and cool place.\u003c\/p\u003e\n\u003cp\u003eKeep out of reach of children.\u003c\/p\u003e\n\u003ch3\u003eDetails\u003c\/h3\u003e\n\u003cp\u003eYesNutri SUPRA NMN 30000+ contains a high content and purity of NMN (Nicotinamide mononucleotide), a biosynthetic precursor of NAD+, which is known to promote the production of NAD+ in cells and counteract the aging-associated diseases associated with the decline in tissue NAD+ levels.\u003csup\u003e14\u003c\/sup\u003e Scientific research shows that NMN can effectively activate cell functions, delay aging, and strengthen the body's ability to repair.\u003csup\u003e12,13,16\u003c\/sup\u003e Nicotinamide adenine dinucleotide (NAD+) is a central signaling molecule involved in cellular processes related to age-related diseases, indicating that NAD+ decline is the main feature of accelerated aging. Certain studies have shown that the NAD+ production mechanism along the age becomes worse and the NAD+ level becomes lower. It has been found that a special transporter (Slc12a8) directly enters the cell to produce NAD+ in the body to maintain the NAD+ level, thereby slowing down the premature aging syndrome and normal aging.\u003csup\u003e14-16\u003c\/sup\u003e\u003c\/p\u003e\n\u003cp\u003eAstaxanthin is extracted from natural Haematococcus pluvialis. Canthaxanthin, beta carotene and lutein naturally exist in Haematococcus pluvialis. The astaxanthin content of Haematococcus pluvialis is more than 10 times that of krill oil.\u003csup\u003e3-6\u003c\/sup\u003e It is scientifically proven that astaxanthin has potent antioxidant and hepatoprotective effect and has high nutritional value.\u003csup\u003e1-2,9,11\u003c\/sup\u003e Astaxanthin has a unique molecular structure, which allows it to have extraordinary chemical properties. It has no less than ten times or higher than other carotenoids such as lutein and β-carotene.\u003csup\u003e1,7,8,10\u003c\/sup\u003e Meanwhile, it can prevent cell membrane oxidation and stop the chain reaction of free radicals.\u003csup\u003e1,7,10,16\u003c\/sup\u003e Astaxanthin can cross the blood-brain barrier and enter the retinal tissue to provide protection for the retina, reduce damage caused by ultraviolet rays, and accelerate recovery, which is very helpful to relieve eye discomfort.\u003c\/p\u003e\n\u003cp\u003eLutein is a natural carotenoid which can be found in the macula and the rest of the retina. Lutein could not be synthesized in mammals and must be obtained from the diet. It is a yellowish pigment which could filter blue light at the high energy end of the visible spectrum, thus reducing UV radiation toxicity to the retina and the skin. At the same time, lutein has antioxidant ability which can protect eyes and skin by reducing oxidative damage to cells.\u003csup\u003e22\u003c\/sup\u003e\u003c\/p\u003e\n\u003cp\u003eResveratrol is a strong natural antioxidant. Resveratrol can activate expression of the longevity gene SIRT1 to slow down aging and help maintain proper cell metabolism.\u003csup\u003e19\u003c\/sup\u003e It can suppress melanin formation beneath skin and reduce dark spots.\u003csup\u003e20\u003c\/sup\u003e Moreover, resveratrol can help the skin resist water loss and pump water back to the cells. It contributes to an overall skin whitening and moisturizing effect.\u003csup\u003e21\u003c\/sup\u003e Anti-oxidizing property of resveratrol allows heart, blood vessels, pancreas, and kidney to stay healthy. Resveratrol can improve energy release from glucose to support daily energy needs.\u003c\/p\u003e\n\u003cp\u003ePQQ is a multifunctional nutrient found in plant-based foods, commonly found in leafy vegetables, fruits, and legumes. It provides extensive benefits for the brain and body, including stimulating mitochondrial biogenesis\u003csup\u003e17\u003c\/sup\u003e, producing nerve growth factor (NGF)\u003csup\u003e18\u003c\/sup\u003e, providing powerful antioxidant activity, reducing inflammation, and extending the lifespan of organs rich in mitochondria such as the heart, brain, liver, and others. Mitochondria produces the vast majority of cellular energy (ATP), playing an important role in our overall health. PQQ stimulates mitochondrial growth and replication\u003csup\u003e17\u003c\/sup\u003e. The more energy produced in cells, the better each organ in the body will function. For example, enhancing brain cell energy will make the brain clearer, and enhancing skin cell energy will make wounds heal faster.\u003c\/p\u003e\n\u003cp\u003eNerve growth factor (NGF) is a protein that plays a crucial role in the growth, development, and maintenance of neurons. Studies have shown that PQQ can promote the production of NGF\u003csup\u003e18\u003c\/sup\u003e. Increasing NGF levels helps maintain the health of the brain and peripheral nerves and stimulates brain cell regeneration.\u003c\/p\u003e\n\u003cp\u003eCoenzyme Q10 is an important antioxidant that protects cells and bodily structures. It can eliminate harmful free radicals within cells, slowing cellular aging. Coenzyme Q10 is widely distributed in the body, with high-energy tissues like the heart, kidneys, liver, and muscles having greater demand for it.\u003csup\u003e23\u003c\/sup\u003e It participates in cellular energy production, assisting metabolism and increasing energy supply to maintain normal bodily functions. Coenzyme Q10 can strengthen the heart, delay vascular aging, and protect cardiovascular health.\u003csup\u003e24\u003c\/sup\u003e It can also enhance muscle endurance, improve physical performance, and maintain mental vitality.\u003csup\u003e25\u003c\/sup\u003e\u003c\/p\u003e\n\u003cp\u003eThe above nutrients are beneficial for slowing down aging, protecting the eyes, skincare, promoting brain health, and improving heart and cardiovascular health. This product is suitable for people who are concerned about these aspects of health.\u003c\/p\u003e\n\u003ch4\u003eReferences\u003c\/h4\u003e\n\u003col\u003e\n\u003cli\u003eAmbati RR, Phang SM, Ravi S, Aswathanarayana RG. Astaxanthin: Sources, Extraction, Stability, Biological Activities and Its Commercial Applications–A Review. Mar Drugs. 2014;12(1):128-52. doi: 10.3390\/md12010128.\u003c\/li\u003e\n\u003cli\u003eKistler A, Liechti H, Pichard L, Wolz E, Oesterhelt G et al. Metabolism and CYP-inducer properties of astaxanthin in man and primary human hepatocytes. Arch Toxicol. 2002;75(11-12):665-75.\u003c\/li\u003e\n\u003cli\u003eLorenz RT, Cysewski GR. Commercial potential for Haematococcous microalgae as a natural source of Astaxanthin. Trends Biotechnol. 2000;18(4):160-7.\u003c\/li\u003e\n\u003cli\u003eKwantes JM, Grundmann O. A brief review of krill oil history, research, and the commercial market. J. Diet Suppl. 2004 Apr 1.\u003c\/li\u003e\n\u003cli\u003eKrill – Marine Lipid Complex Technical Data Sheet. NutriScience Innovations: Product Information. Available online at http:\/\/www.nutriscienceusa.com\/KrillOilMLC.htm\u003c\/li\u003e\n\u003cli\u003eFish oil vs. krill oil. Omega-Research. Available online at http:\/\/www.omega-research.com\/\u003c\/li\u003e\n\u003cli\u003eYuan JP, Peng J, Yin K, Wang JH. Potential health-promoting effects of Astaxanthin: A high-value carotenoid mostly from microalgae. Mol Nutr Food Res. 2011;55(1):150-65.\u003c\/li\u003e\n\u003cli\u003eSpiller GA, Dewell A. Safety of an Astaxanthin-Rich Haematococcus pluvialis Algal Extract: A Randomized Clinical Trial. J Med Food. 2003 Spring;6(1):51-6.\u003c\/li\u003e\n\u003cli\u003eAstaxanthin. Martindale: The Complete Drug Reference. Available online at: http:\/\/www.medicinescomplete.com\u003c\/li\u003e\n\u003cli\u003eKidd P. Astaxanthin, cell membrane nutrient with diverse clinical benefits and anti-aging potential. Altern Med Rev. 2011;16(4):355-64.\u003c\/li\u003e\n\u003cli\u003eFassett RG, Coombes JS. Astaxanthin: A potential therapeutic agent in cardiovascular disease. Mar Drugs. 2011;9(3):447-65.\u003c\/li\u003e\n\u003cli\u003eYoshino J, Baur JA, Imai SI. NAD+ Intermediates: The Biology and Therapeutic Potential of NMN and NR. Cell Metab. 2018 Mar 6;27(3):513-528. doi: 10.1016\/j.cmet.2017.11.002. Epub 2017 Dec 14. PMID: 29249689; PMCID: PMC5842119.\u003c\/li\u003e\n\u003cli\u003eKiss T, Balasubramanian P, Valcarcel-Ares MN, Tarantini S, Yabluchanskiy A, Csipo T, Lipecz A, Reglodi D, Zhang XA, Bari F, Farkas E, Csiszar A, Ungvari Z. Nicotinamide mononucleotide (NMN) treatment attenuates oxidative stress and rescues angiogenic capacity in aged cerebromicrovascular endothelial cells: a potential mechanism for the prevention of vascular cognitive impairment. Geroscience. 2019 Oct;41(5):619-630. doi: 10.1007\/s11357-019-00074-2. Epub 2019 May 29. PMID: 31144244; PMCID: PMC6885080.\u003c\/li\u003e\n\u003cli\u003eGrozio A, Mills KF, Yoshino J, Bruzzone S, Sociali G, Tokizane K, Lei HC, Cunningham R, Sasaki Y, Migaud ME, Imai SI. Slc12a8 is a nicotinamide mononucleotide transporter. Nat Metab. 2019 Jan;1(1):47-57. doi: 10.1038\/s42255-018-0009-4. Epub 2019 Jan 7. Erratum in: Nat Metab. 2019 Jul;1(7):743. PMID: 31131364; PMCID: PMC6530925.\u003c\/li\u003e\n\u003cli\u003eKincaid JW, Berger NA. NAD metabolism in aging and cancer. Experimental Biology and Medicine. 2020;245(17):1594-1614. doi:10.1177\/1535370220929287\u003c\/li\u003e\n\u003cli\u003eKane, A. and D. Sinclair. Sirtuins and NAD+ in the Development and Treatment of Metabolic and Cardiovascular Diseases. Circulation Research .2018(123): 868–885.\u003c\/li\u003e\n\u003cli\u003ePyrroloquinoline Quinone Stimulates Mitochondrial Biogenesis through cAMP Response Element-binding Protein Phosphorylation and Increased PGC-1α Expression. 2009 Oct 27; PMCID: PMC2804159\u003c\/li\u003e\n\u003cli\u003eStimulation of Nerve Growth Factor Production by Pyrroloquinoline Quinone and Its Derivatives in Vitro and in Vivo, Bioscience, Biotechnology, and Biochemistry, 57:7, 1231-1233, DOI: 10.1271\/bbb.57.1231\u003c\/li\u003e\n\u003cli\u003eSarubbo F, Esteban S, Miralles A, Moranta D. Effects of Resveratrol and other Polyphenols on Sirt1: Relevance to Brain Function During Aging. Curr Neuropharmacol. 2018 Jan 30;16(2):126-136. doi: 10.2174\/1570159X15666170703113212. PMID: 28676015; PMCID: PMC5883375.\u003c\/li\u003e\n\u003cli\u003eBoo YC. Human Skin Lightening Efficacy of Resveratrol and Its Analogs: From in Vitro Studies to Cosmetic Applications. Antioxidants (Basel). 2019 Aug 22;8(9):332. doi: 10.3390\/antiox8090332. PMID: 31443469; PMCID: PMC6770230.\u003c\/li\u003e\n\u003cli\u003eXia N, Daiber A, Förstermann U, Li H. Antioxidant effects of resveratrol in the cardiovascular system. Br J Pharmacol. 2017 Jun;174(12):1633-1646. doi: 10.1111\/bph.13492. Epub 2016 May 6. PMID: 27058985; PMCID: PMC5446570.\u003c\/li\u003e\n\u003cli\u003eChae, S. Y., Shin, M. C., Jeon, S., Kang, M. S., Han, D.-W., \u0026amp; Hong, S. W. (2021). A simple route to the complexation of lutein with reduced graphene oxide nanocarriers and antioxidant protection against Blue Light. International Journal of Nanomedicine, Volume 16, 6843–6860. https:\/\/doi.org\/10.2147\/ijn.s320790\u003c\/li\u003e\n\u003cli\u003eBhagavan, H. N., \u0026amp; Chopra, R. K. (2006). Coenzyme Q10: Absorption, tissue uptake, metabolism and pharmacokinetics. Free Radical Research, 40(5), 445–453. https:\/\/doi.org\/10.1080\/10715760600617843\u003c\/li\u003e\n\u003cli\u003eFedacko, J. (2011). Coenzyme Q10 in heart and brain diseases. The Open Nutraceuticals Journal, 4(1), 69–87. https:\/\/doi.org\/10.2174\/1876396001104010069\u003c\/li\u003e\n\u003cli\u003eSiebrecht, S., Chan, D. Y. L., Rosenfeld, F., \u0026amp; Lin, K. W. (2015). Coenzyme Q10 and ubiquinol for physical performance. Coenzyme Q10: From Fact to Fiction; Hargreaves, I., Ed.\u003c\/li\u003e\n\u003c\/ol\u003e","brand":"YesNutri \/ Herb and Nutrition","offers":[{"title":"No outer boxes","offer_id":47881145680023,"sku":null,"price":1580.0,"currency_code":"HKD","in_stock":true},{"title":"Require outer box (it will be provided if available)","offer_id":47881145712791,"sku":null,"price":1580.0,"currency_code":"HKD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0721\/2980\/6487\/files\/SUPRA_NMN30000_main.jpg?v=1780029302"},{"product_id":"yesnutri-supra-nmn-gold-60s-2-boxes-copy","title":"YesNutri Supra NMN Gold","description":"\u003cul\u003e\n\u003cli\u003e\u003cspan\u003eGolden Formula\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003ePromote healthy skin and anti-ageing\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eSupport body muscle recovery from exercise\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eSupport increasing of energy level\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eSupport eye health and help to decelerate aging of vision\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003ePromote general health and wellbeing\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eProduct Introduction\u003c\/h3\u003e\n\u003cp\u003eYesNutri Supra NMN Gold contains four star-ingredients: NMN (nicotinamide mononucleotide), astaxanthin, resveratrol, and PQQ, which enhance anti-aging and reverse aging effects, bringing out a healthy and radiant appearance for you.\u003c\/p\u003e\n\u003cp\u003eNMN – Effectively activates cellular functions, slows down aging, and enhances the body's repairability.\u003c\/p\u003e\n\u003cp\u003eAstaxanthin – Helps maintain eye health and delays visual aging.\u003c\/p\u003e\n\u003cp\u003eResveratrol – Highly moisturizing, enhances skin elasticity, and maintains a youthful appearance.\u003c\/p\u003e\n\u003cp\u003ePQQ – Activates brain cells to have more energy, making the brain more agile and clear, and enhancing memory.\u003c\/p\u003e\n\u003ch3\u003eProduct Name\u003c\/h3\u003e\n\u003cp\u003eYesNutri Supra NMN Gold\u003c\/p\u003e\n\u003ch3\u003ePack Size\u003c\/h3\u003e\n\u003cp\u003e30 Veggie Capsule\u003cbr\u003e60 Veggie Capsule\u003cbr\u003e\u003c\/p\u003e\n\u003ch3\u003ePlace of Origin\u003c\/h3\u003e\n\u003cp\u003eAmerica\u003c\/p\u003e\n\u003ch3\u003eComposition\u003c\/h3\u003e\n\u003cp\u003eEach two capsules contain:\u003c\/p\u003e\n\u003cp\u003eBeta-nicotinamide mononucleotide (NMN) 500mg\u003cbr\u003eResveratrol 50mg\u003cbr\u003ePyrroloquinoline Quinone (PQQ) 50mg\u003cbr\u003eAstaxanthin 4mg\u003cbr\u003eBeta-carotene 64mcg\u003cbr\u003eLutein 60mcg\u003c\/p\u003e\n\u003ch3\u003eDirection\u003c\/h3\u003e\n\u003cp\u003eAdults take 1-2 capsules daily with meal or as recommended by your physicians.\u003c\/p\u003e\n\u003ch3\u003eDescription\u003c\/h3\u003e\n\u003cp\u003eYesNutri SUPRA NMN Gold contains highly concentrated NMN (Nicotinamide mononucleotide), a biosynthetic precursor of NAD+, which is known to promote the production of NAD+ in cells and counteract the aging-associated diseases associated with the decline in tissue NAD+ levels.\u003csup\u003e14\u003c\/sup\u003e Scientific research shows that NMN (Nicotinamide mononucleotide) can effectively activate cell functions, delay aging, and strengthen the body's ability to repair.\u003csup\u003e12,13,16\u003c\/sup\u003e Nicotinamide adenine dinucleotide (NAD+) is a central signaling molecule involved in cellular processes related to age-related diseases, indicating that NAD+ decline is the main feature of accelerated aging. Certain studies have shown that the NAD+ production mechanism along the age becomes worse and the NAD+ level becomes lower. It has been found that a special transporter (Slc12a8) directly enters the cell to produce NAD+ in the body to maintain the NAD+ level, thereby slowing down the premature aging syndrome and normal aging.\u003csup\u003e14-16\u003c\/sup\u003e\u003c\/p\u003e\n\u003cp\u003eAstaxanthin of Yesnutri Supra NMN Gold is extracted from natural Haematococcus pluvialis. The astaxanthin content of Haematococcus pluvialis is more than 10 times that of krill oil.\u003csup\u003e3-6\u003c\/sup\u003e It is scientifically proven that astaxanthin has potent antioxidant and hepatoprotective effect and has high nutritional value.\u003csup\u003e1-2,9,11\u003c\/sup\u003e Astaxanthin has a unique molecular structure, which allows it to have extraordinary chemical properties. It has no less than ten times or higher than other carotenoids such as lutein and β-carotene.\u003csup\u003e1,7,8,10\u003c\/sup\u003e Meanwhile, it can prevent cell membrane oxidation and stop the chain reaction of free radicals.\u003csup\u003e1,7,10,16\u003c\/sup\u003e Astaxanthin can cross the blood-brain barrier and enter the retinal tissue to provide protection for the retina, reduce damage caused by ultraviolet rays, and accelerate recovery, which is very helpful to relieve eye discomfort.\u003c\/p\u003e\n\u003cp\u003eResveratrol is a strong natural antioxidant. Resveratrol can activate expression of the longevity gene SIRT1 to slow down aging and help maintain proper cell metabolism.\u003csup\u003e19\u003c\/sup\u003e It can suppress melanin formation beneath skin and reduce dark spots.\u003csup\u003e20\u003c\/sup\u003e Moreover, resveratrol can help the skin resist water loss and pump water back to the cells. It contributes to an overall skin whitening and moisturizing effect.\u003csup\u003e21\u003c\/sup\u003e Anti-oxidizing property of resveratrol allows heart, blood vessels, pancreas, and kidney to stay healthy. Resveratrol can improve energy release from glucose to support daily energy needs.\u003c\/p\u003e\n\u003cp\u003ePQQ is a multifunctional nutrient found in plant-based foods, commonly found in leafy vegetables, fruits, and legumes. It provides extensive benefits for the brain and body, including stimulating mitochondrial biogenesis\u003csup\u003e17\u003c\/sup\u003e, producing nerve growth factor (NGF)\u003csup\u003e18\u003c\/sup\u003e, providing powerful antioxidant activity, reducing inflammation, and extending the lifespan of organs rich in mitochondria such as the heart, brain, liver, and others. Mitochondria produces the vast majority of cellular energy (ATP), playing an important role in our overall health. PQQ stimulates mitochondrial growth and replication\u003csup\u003e17\u003c\/sup\u003e. More mitochondria will produce more cellular energy (ATP) production, and the more energy in cells, the better each organ in the body will function. For example, enhancing brain cell energy will make the brain clearer, and enhancing skin cell energy will make wounds heal faster. Nerve growth factor (NGF) is a protein that plays a crucial role in the growth, development, and maintenance of neurons. Studies have shown that PQQ can promote the production of NGF\u003csup\u003e18\u003c\/sup\u003e. Increasing NGF levels helps maintain the health of the brain and peripheral nerves and stimulates brain cell regeneration.\u003c\/p\u003e\n\u003ch4\u003eBenefit of Lutein\u003c\/h4\u003e\n\u003cp\u003eLutein is a natural carotenoid which can be found in the macula and the rest of the retina. Lutein could not be synthesized in mammals and must be obtained from the diet. It is a yellowish pigment which could filter blue light at the high energy end of the visible spectrum, thus reducing UV radiation toxicity to the retina and the skin. At the same time, lutein has antioxidant ability which can protect eyes and skin by reducing oxidative damage to cells.\u003c\/p\u003e\n\u003cp\u003eThe above nutrients are beneficial for slowing down aging, protecting the eyes, skincare, promoting brain health, and improving heart and cardiovascular health. They are suitable for people who are concerned about these aspects of health.\u003c\/p\u003e\n\u003ch4\u003e參考文獻：\u003c\/h4\u003e\n\u003ch4\u003eReferences\u003c\/h4\u003e\n\u003col\u003e\n\u003cli\u003eAmbati RR, Phang SM, Ravi S, Aswathanarayana RG. Astaxanthin: Sources, Extraction, Stability, Biological Activities and Its Commercial Applications–A Review. Mar Drugs. 2014;12(1):128-52. doi: 10.3390\/md12010128.\u003c\/li\u003e\n\u003cli\u003eKistler A, Liechti H, Pichard L, Wolz E, Oesterhelt G et al. Metabolism and CYP-inducer properties of astaxanthin in man and primary human hepatocytes. Arch Toxicol. 2002;75(11-12):665-75.\u003c\/li\u003e\n\u003cli\u003eLorenz RT, Cysewski GR. Commercial potential for Haematococcous microalgae as a natural source of Astaxanthin. Trends Biotechnol. 2000;18(4):160-7.\u003c\/li\u003e\n\u003cli\u003eKwantes JM, Grundmann O. A brief review of krill oil history, research, and the commercial market. J. Diet Suppl. 2004 Apr 1.\u003c\/li\u003e\n\u003cli\u003eKrill – Marine Lipid Complex Technical Data Sheet. NutriScience Innovations: Product Information. Available online at http:\/\/www.nutriscienceusa.com\/KrillOilMLC.htm\u003c\/li\u003e\n\u003cli\u003eFish oil vs. krill oil. Omega-Research. Available online at http:\/\/www.omega-research.com\/\u003c\/li\u003e\n\u003cli\u003eYuan JP, Peng J, Yin K, Wang JH. Potential health-promoting effects of Astaxanthin: A high-value carotenoid mostly from microalgae. Mol Nutr Food Res. 2011;55(1):150-65.\u003c\/li\u003e\n\u003cli\u003eSpiller GA, Dewell A. Safety of an Astaxanthin-Rich Haematococcus pluvialis Algal Extract: A Randomized Clinical Trial. J Med Food. 2003 Spring;6(1):51-6.\u003c\/li\u003e\n\u003cli\u003eAstaxanthin. Martindale: The Complete Drug Reference. Available online at: http:\/\/www.medicinescomplete.com\u003c\/li\u003e\n\u003cli\u003eKidd P. Astaxanthin, cell membrane nutrient with diverse clinical benefits and anti-aging potential. Altern Med Rev. 2011;16(4):355-64.\u003c\/li\u003e\n\u003cli\u003eFassett RG, Coombes JS. Astaxanthin: A potential therapeutic agent in cardiovascular disease. Mar Drugs. 2011;9(3):447-65.\u003c\/li\u003e\n\u003cli\u003eYoshino J, Baur JA, Imai SI. NAD+ Intermediates: The Biology and Therapeutic Potential of NMN and NR. Cell Metab. 2018 Mar 6;27(3):513-528. doi: 10.1016\/j.cmet.2017.11.002. Epub 2017 Dec 14. PMID: 29249689; PMCID: PMC5842119.\u003c\/li\u003e\n\u003cli\u003eKiss T, Balasubramanian P, Valcarcel-Ares MN, Tarantini S, Yabluchanskiy A, Csipo T, Lipecz A, Reglodi D, Zhang XA, Bari F, Farkas E, Csiszar A, Ungvari Z. Nicotinamide mononucleotide (NMN) treatment attenuates oxidative stress and rescues angiogenic capacity in aged cerebromicrovascular endothelial cells: a potential mechanism for the prevention of vascular cognitive impairment. Geroscience. 2019 Oct;41(5):619-630. doi: 10.1007\/s11357-019-00074-2. Epub 2019 May 29. PMID: 31144244; PMCID: PMC6885080.\u003c\/li\u003e\n\u003cli\u003eGrozio A, Mills KF, Yoshino J, Bruzzone S, Sociali G, Tokizane K, Lei HC, Cunningham R, Sasaki Y, Migaud ME, Imai SI. Slc12a8 is a nicotinamide mononucleotide transporter. Nat Metab. 2019 Jan;1(1):47-57. doi: 10.1038\/s42255-018-0009-4. Epub 2019 Jan 7. Erratum in: Nat Metab. 2019 Jul;1(7):743. PMID: 31131364; PMCID: PMC6530925.\u003c\/li\u003e\n\u003cli\u003eKincaid JW, Berger NA. NAD metabolism in aging and cancer. Experimental Biology and Medicine. 2020;245(17):1594-1614. doi:10.1177\/1535370220929287\u003c\/li\u003e\n\u003cli\u003eKane, A. and D. Sinclair. Sirtuins and NAD+ in the Development and Treatment of Metabolic and Cardiovascular Diseases. Circulation Research .2018(123): 868–885.\u003c\/li\u003e\n\u003cli\u003ePyrroloquinoline Quinone Stimulates Mitochondrial Biogenesis through cAMP Response Element-binding Protein Phosphorylation and Increased PGC-1α Expression. 2009 Oct 27; PMCID: PMC2804159\u003c\/li\u003e\n\u003cli\u003eStimulation of Nerve Growth Factor Production by Pyrroloquinoline Quinone and Its Derivatives in Vitro and in Vivo, Bioscience, Biotechnology, and Biochemistry, 57:7, 1231-1233, DOI: 10.1271\/bbb.57.1231\u003c\/li\u003e\n\u003cli\u003eSarubbo F, Esteban S, Miralles A, Moranta D. Effects of Resveratrol and other Polyphenols on Sirt1: Relevance to Brain Function During Aging. Curr Neuropharmacol. 2018 Jan 30;16(2):126-136. doi: 10.2174\/1570159X15666170703113212. PMID: 28676015; PMCID: PMC5883375.\u003c\/li\u003e\n\u003cli\u003eBoo YC. Human Skin Lightening Efficacy of Resveratrol and Its Analogs: From in Vitro Studies to Cosmetic Applications. Antioxidants (Basel). 2019 Aug 22;8(9):332. doi: 10.3390\/antiox8090332. PMID: 31443469; PMCID: PMC6770230.\u003c\/li\u003e\n\u003cli\u003eXia N, Daiber A, Förstermann U, Li H. Antioxidant effects of resveratrol in the cardiovascular system. Br J Pharmacol. 2017 Jun;174(12):1633-1646. doi: 10.1111\/bph.13492. Epub 2016 May 6. PMID: 27058985; PMCID: PMC5446570.\u003c\/li\u003e\n\u003c\/ol\u003e","brand":"YesNutri \/ Herb and Nutrition","offers":[{"title":"30 Tablets \/ No outer boxes","offer_id":47861680799895,"sku":null,"price":980.0,"currency_code":"HKD","in_stock":true},{"title":"30 Tablets \/ Require outer box (it will be provided if available)","offer_id":47861680832663,"sku":null,"price":980.0,"currency_code":"HKD","in_stock":true},{"title":"60 Tablets \/ No outer boxes","offer_id":47861680865431,"sku":null,"price":1580.0,"currency_code":"HKD","in_stock":true},{"title":"60 Tablets \/ Require outer box (it will be provided if available)","offer_id":47861680898199,"sku":null,"price":1580.0,"currency_code":"HKD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0721\/2980\/6487\/files\/SUPRA_NMN_GOLD_Chin_main.jpg?v=1781755314"}],"url":"https:\/\/yesnutri.com\/en\/collections\/best-buy.oembed","provider":"YesNutri","version":"1.0","type":"link"}